Materno-Fetal Haematological Relationship In Malaria At Mongomo, Guinea Equatoria

AAG Jimoh



This study is aimed to determine the effects of maternal and fetal parasitaemia on maternal and fetal haemoglobin. A nine-month (January – September 1997) prospective study was carried out at the labour unit of the Regional Hospital in Mongomo, Guinea Equatoria. One hundred and twenty-four patients with singleton deliveries were studied. The prevalence rate of maternal and fetal parasitaemia were 102 (82.25%) and 33 (26.61%) respectively. The mean maternal haemoglobin was 10.11 + 1.35 gm/dl, those with parasitaemia 9.26+0.85 gm/dl and those without parasitaemia 11.45+1.20 gm/dl (p<0.005). There is a close correlation between maternal parasitaemia, worsening maternal haemoglobin level and fatal parasitaemia (p<0.005 df=3 95% CI). Fetal parasitaemia is significantly commoner in fetuses with severe anaemia compared to those with negative fatal parasitaemia (p<0.005). The author emphasized curative treatment of all pregnant women at the first antenatal care visit to be supplemented by adequate prophylaxis throughout pregnancy. Choice of drugs for treatment and prophylaxis must be guided by the local sensitivity patterns and safety profiles of the drugs to the mothers and the developing fetuses.

Afr. J. Clin. Exper. Microbiol. 2004; 5 (3): 217-220

Prevalence And Distribution Of Ruminant Trypanosomosis In Bokkos Local Government Area Of Plateau State, Nigeria

JO Kalajaiye, SO Omotainse, GA Omoogun



The seasonal prevalence of typanosomosis was investigated in Bokkos LGA of Plateau State, Nigeria. A total of 740 animals (684 cattle and 56 sheep) were bled during the dry and wet seasons. The standard methods used were simple random and jugular venipucture. Standard parasitological methods were used to determine the infection rate. In cattle, the findings showed an infection rate of 11.7% while in sheep it was 17.9%. Peak infection in animals was during the end of the rainy season and beginning of dry season (September-December). Complementary mice inoculation tests revealed 83 sub patent cases and are recommended as a confirmatory diagnostic technique.

Afr. J. Clin. Exper. Microbiol. 2004; 5 (3): 221-224

Changes In Peripheral Leukocyte And Body Fluids Of Onchocerciasis Patients Treated With Ivermectin

OU Manafa, MA Mafe, ET Idowu, MB Ajayi



This study evaluated the peripheral leukocyte count and the presence of microfilariae in the body fluids of onchocerciasis patients treated with ivermectin. Fifty-three patients over the age 10 years were selected from Ipogun, an onchocerciasis endemic area in Ondo State, Nigeria. Before and after treatment, all patients received a parasitologic and clinical examination that included physical examination, palpation of onchocercal nodules, assessment of microfilarial densities in iliac crest skin snips, diagnosis of concomitant parasitic infections in stool specimens and total leukocytes differential counts. Results indicated that ivermectin did not induce a decrease in the total number of peripheral leukocytes but there was a decrease in the number of eosinophils. Microfilariae were not found in increase frequency in the urine, blood and sputum, while the number of microfilariae per mg of skin snip decreased.

Afr. J. Clin. Exper. Microbiol. 2004; 5 (3): 225-230