Recent rubella infection among childbearing women in a tertiary hospital in Nigeria: A seroepidemiological indication for vaccination need

ST Suleiman, R Bakare, AA Akanbi, A Fowotade, SA Billiaminu, KA Durowade



Background: Congenital Rubella Infection can be prevented and future generation saved from  disability by protecting women of reproductive age through vaccination. The study is aimed at  determining serological evidence of recent rubella infection among women of childbearing age.
Method: A cross sectional study was carried out among 285 women aged between 15 and 49 years. Enzyme immunoassay method was used to detect and quantify human IgM and IgG antibodies with avidity for Rubella virus in sera of participants. Socio-demographic characteristics of the subjects, along with recent history of fever, rash and adverse pregnancy outcome among others were obtained using a questionnaire. Statistical analysis was carried out using the program statistical package for social sciences (SPSS) version 16. Majority (78.3%) of the women recruited for the study were within 15-34 years age range. Of the 285 sera assayed for Rubella IgM antibodies, 23 (8.1%; 95% CI: 4.9%-11.3 %.) was IgM seropositive, while the remaining 262 (91.9%) were seronegative. A total of 7 (2.5%) of reproductive age women in Ilorin had a recent primary infection while 16 (5.6%) had a persistent Rubella infection or recent re-infection.
In conclusion, there is need for vaccination of susceptible women of reproductive age in Ilorin as a large number of women have Rubella in their reproductive age.

Keywords: Rubella, Immunoglobulin M, avidity, reproductive age, Ilorin, Nigeria

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Recent rubella infection among childbearing women in a tertiary hospital in Nigeria A seroepidemiological indication for vaccination need

Sexual Behaviour And Condom Use Among Nigerian Soldiers In Ilorin, Kwara State, Nigeria

NAA Hussain, TM Akande



Background/Objective: Studies have shown that military personnel are aware and knowledgeable about HIV/AIDS and its impact on combat preparedness and efficiency. However, this knowledge did not appear to have translated to reduced risky sexual behaviours. This study, therefore aimed at determining the sexual behaviour and condom use among Nigerian Army personnel in Ilorin, Nigeria. Materials and methods: A descriptive cross-sectional study using a multistage sampling technique to select 400 participants. A pre-tested semi-structured questionnaire was administered. Results: Out of 386 respondents (response rate 96.5%) males constituted 91.2%. Two hundred and
seventy two (70.5 %) were married while 42 (15.4%) of the married did not live with their spouses. A significant proportion of the respondents (45.5%), especially those within the age of 18 to 34 years (p=0.000), those who had participated in foreign military operations (p=0.030) and those who did not live with their spouses (p=0.000) engaged in pre/extramarital sexual activities. Regular condom use among the respondents was low.
Conclusion/Recommendations: There was a high risky sexual behaviour with irregular condom use among the study population. A continuous information, education and communication on HIV/AIDS to effect safe sex behaviours and regular condom use among this population are recommended.

Keywords: Sexual, Behaviour, Condom, Nigerian, Soldiers, Ilorin

African Journal of Clinical and Experimental Microbiology Vol. 10 (2) 2009: pp. 128-135


SS Taiwo, BA Onile, AA Akanbi II



Nosocomial infections caused by methicillin-resistant strains of Staphylococcus aureus often pose therapeutic dilemma to the clinicians because of the multi resistant nature of these strains of Staphylococcus aureus. Outbreaks of both nosocomial and community acquired infections are also frequent and difficult to control. This study determined the prevalence and antimicrobial susceptibility pattern of methicillin-resistant Staphylococcus aureus (MRSA) at the University of Ilorin Teaching Hospital, between January and December 2001. The methicillin disc diffusion method for the detection of methicillin resistance and the Kirby-Bauer disc diffusion for antibiotic susceptibility tests, were used. The MRSA prevalence rate was 34.7% (51/147) of all Staphylococcus aureus isolates. Forty-five isolates were associated with infections and 6 were colonizing strains. Thirty-six (70.6%) were hospital (nosocomial) acquired while 15 (29.4%) were community-acquired. Forty-eight patients have received antibiotics previously including 30 who had received multiple antibiotics. Skin and soft tissues were sites of infections in 36 cases and surgical, emergency and intensive care units accounted for 31 isolates. All MRSA isolates were resistant to more than two antibiotics but remained largely susceptible to third generation cephalosporins, macrolides and quinolones and all were sensitive to vancomycin. We recommend the use of third generation cephalosporins and quinolones where indicated, in the treatment of serious MRSA infections in this environment. Control of the spread of MRSA in this hospital must include reinforcement of appropriate use of antibiotics, hand washing and laboratory surveillance for MRSA, particularly in the surgical wards and intensive care units, in order to identify sources of outbreaks.

Key Words: Methicillin-resistant, Staphylococcus aureus, Ilorin.

Afr. J. Clin. Exper. Microbiol. 2004; 5(2): 189 – 197.