Nosocomial Urinary Infections at the Urogoly Unit of the National University Hospital (Yalgado Ouedraogo), Ouagadougou: Feb.-Sept. 2012

I Sanou, A Kabore, E Tapsoba, I Bicaba, A Ba, B Zango

 

Abstract

Objective: The aim of this study was to identify the risk factors and the microorganisms susceptibilities of nosocomial urinary infections at the urology unit of the national university hospital of Ouagadougou in Burkina Faso.
Method: From February to September 2012, two bacteriological analyzes have been performed for any of the 75 inpatients in the urology unit of the national university hospital of Ouagadougou in Burkina Faso.
Results: During the study period, 43 cases of nosocomial urinary infection were identified (57.3%) and we found no statistically significant associated risk factors with age groups, sex, arterial blood pressure, kidney illness and urinary obstructive pathologies.
The most frequently isolated bacteria were Escherichia coli (30.9%),  Klebsiella spp (26.9%) and Staphylococcus spp (15.4%). The yeasts strains were very sensitive to antifungal but the bacteria susceptibility rate to antibiotics was very variable. Thus, the cocci were rather sensitive to  association clavulanic acid + amoxicilline and ceftriaxone and enough
sensitive to gentamicine ; the bacilli were enough sensitive to gentamicin and very sensitive to imipenem.
Conclusion: From the antibiogram results, we recommend gentamicin in combination with penicillin or metronidazole as the first antibiotics to be used in the treatment of nosocomial urinary tract infections.

Keywords: urinary infection, nosocomial infection, bacteria, antibiotics

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Nosocomial Urinary Infections at the Urogoly Unit of the National University Hospital Yalgado Ouedraogo Ouagadougou Feb Sept 2012

Urinary Tract Infections amongst Pregnant Women Attending A Medical Centre IN Kaduna, Nigeria

M Muhammed

 

Abstract

Urinary tract infection (UTI) constitutes a major health problem in pregnant women due to their relatively short urethra, which promotes the ascending of the pathogens to the bladder, urethra and the kidneys. It is also more common in pregnant women due to the anatomical and physiological changes that occur during pregnancy.
Aim: To determine the incidence of Urinary Tract Infections and the antimicrobial susceptibility of the microbial isolates from the urine samples of pregnant women prior to treatment.
Methods: Fifty (50) mid stream urine (MSU) samples were collected and analyzed using standard Microbiological Techniques, and the antimicrobial sensitivity tests determined using Kirby Bauer disc diffusion techniques.
Results: Of the 50 urine samples obtained from pregnant women, 3 different microbes were isolated indicating 28%. Staphylococcus aureus18%, Escherichia coli 8%, Candida albicans 4%; and a 2% co-infection of Candida albicans and Staphylococcus aureusStaphylococcus aureusand Escherichia coli were highly sensitive to Ciprofloxacin, Ofloxacin (Cilox), Paflacin and
Cephalosporine.
Conclusion: Undetected and untreated urinary tract infection in pregnancy leads to discomfort associated with abdominal pains, itching, vaginal discharge and dysuria which may lead to more serious medical  complications.

Keywords: Microbial isolates; pregnant women; anti-microbial  susceptibility; microbiological techniques; Disc diffusion.

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Urinary Tract Infections amongst Pregnant Women Attending A Medical Centre IN Kaduna Nigeria

Antimicrobial Susceptibility Pattern of Urinary Pathogens Isolated from Two Tertiary Hospitals in Southwestern Nigeria

NS Ochada, IA Nasiru, Y Thairu, MB Okanlowan, YO Abdulakeem

 

Abstract

Background: Urinary tract infection (UTI) is among the most common reasons for patients to seek health assistance that is commonly  encountered in office practices. This is also a leading cause of Gram negative sepsis in hospitalized patients.
Objectives: This study was carried out in order to isolate, characterize and identify the pathogens associated with UTI in two teaching hospitals at Osun state, Nigeria and to determine their antimicrobial susceptibility patterns.
Methods: This was a prospective observational study involving standard microbiological procedures for analysing urine samples of inpatient and outpatient cases of UTI. Identification of these pathogens was performed using Microbact/API identification system.
Results: Out of the 300 urine samples cultured, 88 (29.3%) yielded  significant growth of urinary pathogens while 212 (70.7%) yielded either insignificant growth or no growth of any urinary pathogen. Escherichia coli 19 (21.6%) were the commonest pathogen isolated followed by Klebsiella pneumonia 14 (15.9%), Staphylococcus aureus 12(13.6%), Candida albicans 12(13.6%), Pseudomonas aerugenosa 9 (10.2%), Klebsiella oxytoca 8 (9.1%), Staphylococcus saprophyticus 6 (6.8%), Serratia  rubidaea 3 (3.4%), Enterobacter agglomerans 2 (2.3%), Acinetobacter iwoffii 1 (1.1%), Acinetobacter baumannii 1 (1.1%), Providencia retgerri 1 (1.1%). The susceptibility of Gram negative bacteria (GNB) were mainly toward parenteral antibiotic rather than oral one, while most of the common  antibiotic showed a resistant pattern. UTI was more prevalent among  patients within hospital setting 71(80.7%) than out-patients 17(19.3%).
Conclusion: This study justifies the necessity to treat patients with UTI based on antimicrobial susceptibility test result in order to prevent   evolution of resistant pathogens. Since UTI has large impact on the socio-economy and emergence of bacterial resistance, periodic surveillance of antibiotic susceptibility is strongly recommended.

Keywords: Microbact; antimicrobial resistance; UTI and Osobgo.

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Antimicrobial Susceptibility Pattern of Urinary Pathogens Isolated from Two Tertiary Hospitals in Southwestern Nigeria