E.S Kolade



An increasing number of babies with conjunctivitis in our center what require an urgent evaluation was observed. To evaluate Chlamydial aetiology of Neonatal conjunctivitis in our environment all babies born in the University of Ilorin Teaching Hospital over a six months period were prospectively screened for Neonatal conjunctivitis using the Center for Disease Control/World Health Organization case definition for Neonatal conjunctivitis. All patients diagnosed to have Neonatal conjunctivitis had laboratory evaluation done to identify the causes. However only those from whom the inclusion bodies of chlamydia were seen got included in this study. An empirical treatment with 10% sodium sulphacetamide eye drops was given to all patients while other additional illnesses identified were managed in a standard way. Clinical re-evaluation was done by 72 hours and 7 days of treatment for clinical cure.
A total number of 112 babies developed neonatal conjunctivitis within the study period among the 852 babies screened and chlamydia was seen in 36 (32%). The hospital based incidence for Chlamydial neonatal conjunctivitis was 42 per thousand live births. There was a male preponderance. Gestational Age ranged between 27 weeks and 44 weeks though there were more term babies. Majority were delivered by spontaneous vertex. The Mean Age of on-set of disease was 5 days with a standard deviation of 3.8 days. Premature rupture of fetal membrane occurred in 1 (3%) case. Fifteen (42%) of 36 mothers had antenatal vaginal discharge. All mothers were married. Purulent eye discharge was the commonest clinical presentation and was sometimes unilateral. All babies responded well to treatment. No complication was observed in any baby. It was concluded that chlamydia trachomatis was the leading cause of neonatal conjunctivitis in our environment and the disease is of a remarkable magnitude requiring attention in our sub region. It has similar outlook with those reported from other regions of the World.

(Af. J. of Clinical and Experimental Microbiology: 2002 3(2): 69-71)


R.A. Bakare, A.A. Oni, U.S. Umar, S.A. Fayemiwo, N.A. Fasina, I.F. Adewole, W.A. Shokunbi



Our main objectives was to determine the prevalence of Trichomonas vaginalis among commercial sex workers (CSW’s) in Ibadan, Nigeria. One hundred and sixty nine CSW’s randomly selected from 18 brothels and 136 female patients without symptoms were investigated for Trichomonas vaginalis using both direct microscopy and culture methods. Thirty-seven (21.9%) of the 169 CSW’s investigated had Trichomonas whilst 26(19.1%) of the 136 control subjects were positive for Trichomonas vaginalis. There was no significant difference between the CSW’s with Trichomonas and the control group (p>0.001). We found no association between T. vaginalis and HIV diagnosed in the CSW’s investigated. The age range of peak incidence among the CSWs and the control subjects investigated was 20-29 years. While only 6(3.6%) of the CSWs investigated were married, 88(52.1%) were single, 37 (21.8%) separated, 28 (16.6%) divorced and 10(5.9%) widowed. There was no significant difference between the CSW’s with vaginal Candidiasis, Gonorrhoea and the control group but genital ulcers and HIV positively were significantly higher (p=0.000) in CSW’s than the control subjects. These findings suggest that women who exchange sexual services for money can no longer be ignored. They should be involved in the control and prevention of STDs.
(Af. J. of Clinical and Experimental Microbiology: 2002 3(2): 72-77)


B.A Onile



The sexually Transmitted Diseases constitute major public health problems in Nigeria. There is early sexual maturity and considerable sexual activity between 9 and 15 years of age. Although there is a high awareness of the condom, people are unwilling to use them despite evidence of multiple sexual exposures.
The STDs, including HIV infections, are on the increase. Tuberculosis is also on the increase because of a HIV/AIDS epidemic. Both categorical and integrated approach to the management of STDs and AIDS are being recommended. There is a need to step up basic research into the biology of HIV and subsidize the treatment of AIDS. Efforts at vaccine development should be initiated to stem the worsening HIV epidemic.

(Af. J. of Clinical and Experimental Microbiology: 2002 3(2): 78-81)