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Blood culture contamination in Babcock University Teaching Hospital, Nigeria: A five-year retrospective study

1,2Oluwole, T. O., *1,2Otaigbe, I. I., 1Okunbor, H. N., 1Osinowo, A. O., and 1,2Elikwu, C. J.

1Department of Medical Microbiology and Parasitology, Babcock University Teaching Hospital, Ilishan-Remo, Ogun State, Nigeria
2Department of Medical Microbiology and Parasitology, Benjamin (S) Carson (Snr) College of Health and Medical Sciences, Babcock University, Ilishan-Remo, Ogun State, Nigeria

*Correspondence to: otaigbei@babcock.edu.ng; +2348024406763

Abstract:
Background: Bloodstream infections are a leading cause of morbidity and mortality among in-patients globally. Blood culture is the ‘gold standard’ test for the diagnosis of bloodstream infections. The value of this valuable investigation in the diagnosis of infections however may be affected when an organism of questionable evidence is isolated, which occurs mainly due to contamination during the pre-analytical phase. Blood culture contamination can lead to the administration of unnecessary antibiotics, wastage of hospital resources, and risks to patient life. Hence, this study aimed to analyse the blood culture contamination rate in a private tertiary hospital in southwest Nigeria. Continue reading “Blood culture contamination in Babcock University Teaching Hospital, Nigeria: A five-year retrospective study”

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Candida bloodstream infection among immunocompromised paediatric patients admitted to the University College Hospital, Ibadan, Nigeria

*1Anozie, C. E., 2Okesola, A., 3Makanjuola, O., 4Ayanbekun, T., 5Mohammed, A. R., and 6Fasuyi, T.

1Department of Medical Microbiology, Federal Medical Centre, Umuahia, Nigeria

2Department of Medical Microbiology and Parasitology, University College Hospital Ibadan, Nigeria

3Department of Medical Microbiology and Parasitology, University College Hospital Ibadan, Nigeria

4Department of Medical Microbiology, Federal Medical Centre, Bida, Niger State, Nigeria

5Department of Medical Microbiology, Lead City University, Ibadan, Nigeria 6Department of Medical Microbiology, Babcock University, Ilishan Remo, Ogun State, Nigeria

*Correspondence to: anoziechikezie@gmail.com; 08035607642

Abstract:
Background: Invasive candidiasis is a major hospital acquired fungal infection in Nigeria. Despite advances in support of critically ill patients, candidaemia is still associated with high morbidity and mortality. Data on Candida bloodstream infection among paediatric patients is limited in Nigeria and this informed this study, which was undertaken to investigate the prevalence, species distribution, antifungal susceptibility pattern for blood stream infections due to Candida species in University College Hospital, Ibadan, Nigeria. Continue reading “Candida bloodstream infection among immunocompromised paediatric patients admitted to the University College Hospital, Ibadan, Nigeria”

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Draft metagenome-assembled genomes of Pseudomonas putida isolated from human gut microbiome in Nasarawa State, Nigeria

Anunobi, Oluchukwu Ogechukwu

Department of Biochemistry, Faculty of Science, Bingham University, Karu, Nasarawa State, Nigeria

Correspondence to: oluchukwu.anunobi@binghamuni.edu.ng; 07034439524; ORCID: 0000-0003-2047-5313

Abstract:
The metagenome-assembled genome (MAG) sequences of Pseudomonas putida PP14A and PP20A were obtained by metagenomic sequencing from the gut microbiomes of a female and a male patient both 24 years old from the same household presenting to a health outreach laboratory with complaint of headache, and occasional diarrhoea in Mararaba, Nasarawa State, Nigeria. The phylogenetic relationship observed between the two PP MAGs with other Pseudomonas spp MAGs from human, points to the global spread of Pseudomonas putida through human activity and migration. Continue reading “Draft metagenome-assembled genomes of Pseudomonas putida isolated from human gut microbiome in Nasarawa State, Nigeria”