*Oyedele, A. O., and Akinkunmi, E. O.
Department of Pharmaceutics, Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife, Nigeria
*Correspondence to: aoyedele@oauife.edu.ng
Abstract:
Background: Benzoic acid (BA) and salicylic acid (SA) combined are used as choice topical treatment for fungal and bacterial infections but their delivery is affected by ointment vehicle, among other factors. With aim to achieve improved release and antimicrobial activity in ointment formulation of these medicaments through selection of more efficient vehicle(s), this study comparatively evaluated prospective alternatives to the compendium-specified base for delivery potential and relevant physical properties. Continue reading “Comparative evaluation of hydrophilic bases for improved delivery of Benzoic acid and Salicylic acid in antimicrobial ointment”