*1Afolami, O. I., 2Arogunjo, A. O., 2Oladunmoye, M. K., 3Owoyemi, O. O., 2Aribisala, J. O., 2Ajayi-Moses, O. B., 2Gabriel, P. O., 2Bhadmus, O. C., 2Wasiu, O. S., 2Arogundade, I. O., 2Aiyenuro, E. A., and 2Akinwumi, I. M.
1Department of Biological Sciences, Michigan Technological University, 49931, Houghton, MI, USA
2Department of Microbiology, Federal University of Technology, P.M.B. 704, Akure, Ondo State, Nigeria
3Department of Microbiology, Achievers University, P. M. B. 1030, Owo, Ondo State, Nigeria
Correspondence to: afolamiolufemiifeoluwa@gmail.com or oafolami@mtu.edu
Abstract:
Background: Residents in a rural suburb of Akure jettisoned antibiotic treatment; sought alternative cure to rising incidence of paediatric infections in 2017 from local herbal dealers, with many residents claiming of better treatment response. We investigated these claims since the local herbal formula included kola nut barks and ground termites.
Methodology: Microorganisms associated with termite nests on kola nut trees in the affected community were characterized and identified using standard techniques. The Kirby Bauer disk diffusion was used to evaluate the susceptibility of the bacterial isolates to selected antibiotics. Plasmid profile of multiple antibiotic resistant bacterial isolates (MDRIs) was determined by the Birnboim and Doly method while post plasmid curing antibiotic susceptibility was performed on the MDRIs against the same selected antibiotics. The microorganisms were also evaluated for possible antagonistic effects against Salmonella sp, Staphylococcus aureus and Streptococcus pyogenes isolated from paediatric patients during the period of study using previously described methods. Continue reading “Lactobacillus sp and some fungi from termite nests on kolanut trees had mild antagonistic effects against pathogens isolated from paediatric patients”