The influence of exposure to various concentrations of five antimicrobial agents on intracellular cytotoxin B production in Clostridioides difficile

1Jamal, W., 2Duerden, B. I., and *3Rotimi, V. O.

1Department of Microbiology, College of Medicine, Kuwait University, Kuwait

2Department of Medical Microbiology, University of Wales, Cardiff, United Kingdom

3Center for Infection Control and Patient Safety, College of Medicine University of Lagos, Nigeria

*Correspondence to: bunmivr@yahoo.com

 

Abstract:

 Background: Clostridioides difficile is an important cause of healthcare-associated diarrhea. Several anti- microbial agents are known to promote C. difficile infection (CDI). The impact of various concentrations of ampicillin (AMP), cefotaxime (CTX), clindamycin (CC), metronidazole (MTZ) and vancomycin (VAN) on intracellular cytotoxin B production was investigated in this study. Continue reading “The influence of exposure to various concentrations of five antimicrobial agents on intracellular cytotoxin B production in Clostridioides difficile”