*1Oladejo, O. J., 2Oladejo, J. M., 3Aina, A., 4Oladejo, P., 4Odetoyin, B., 2Oluwaloniola, V., and 2Tangkat, T.
1Department of Ophthalmology, LAUTECH Teaching Hospital, Ogbomoso, Nigeria
2Department of Microbiology and Parasitology, University of Ilorin Teaching Hospital, Ilorin, Nigeria
3Deparrment of Ophthalmology, Bowen University Teaching Hospital, Ogbomoso, Nigeria
4Department of Microbiology, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria *Correspondence to: olawalejob4@gmail.com
Abstract:
Background: Infectious keratitis is a major cause of global blindness. Standard management approaches typically involve the collection of corneal cultures and initiation of broad-spectrum antimicrobials. However, conventional microbiological techniques, based on direct visualization or cultures of microorganisms, are limited by poor sensitivity and the prolonged time required to produce actionable results. Molecular methods based on nucleic acid amplification technique aim to circumvent the challenges of culture for hours or days. The objectives of this study are to detect the bacteria agents of infectious keratitis in Ilorin, Nigeria, using phenotypic and molecular methods, and to determine their resistance profiles to selected antimicrobials. Continue reading “Phenotypic and genotypic detection of antimicrobial-resistant bacterial pathogens from patients with infectious keratitis in selected hospitals in Ilorin, Nigeria”