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Post-exposure prophylaxis for HIV: A 10-year review of data from a tertiary health facility in northcentral Nigeria

*[1]Audu, E. S., [2]Bello, S. O., [3]Ablaku, A., [4]Audu, A. A., 5Bako, I. A., 5Mathew, M., and 6Anazodo, M. C.

1Department of Medical Microbiology, Dalhatu Araf Specialist Hospital, Lafia, Nasarawa State, Nigeria

2Department of Paediatrics, Dalhatu Araf Specialist Hospital, Lafia, Nasarawa State, Nigeria

3Pharmacy Unit, Special Treatment Clinic, Dalhatu Araf Specialist Hospital, Lafia, Nasarawa State, Nigeria

4Department of Human Anatomy, Federal University, Lafia, Nasarawa State, Nigeria

5Department of Community Medicine, Federal University, Lafia, Nasarawa State, Nigeria

6Department of Community Medicine, Dalhatu Araf Specialist Hospital, Lafia, Nasarawa State, Nigeria *Correspondence to: estanamo@gmail.com; +2347083599740 ORCID: 0000-0002-3129-7754

Abstract:  

Background: Post-exposure prophylaxis (PEP) for human immunodeficiency virus (HIV) is the use of short-term antiretroviral therapy (ART) following a single risk exposure to a potential source of HIV infection. If commenced within 72 hours following exposure, PEP has been reported to be very effective in preventing replication and spread of the virus and therefore prevent acquisition of infection. PEP is recommended for exposures occurring in both occupational and non-occupational settings. The objectives of this study are to review the profile of patients and determine the reasons for accessing PEP services in our facility with a view to recommending evidence-based solutions and ultimately contributing to achieving zero transmission of HIV.   Continue reading “Post-exposure prophylaxis for HIV: A 10-year review of data from a tertiary health facility in northcentral Nigeria”

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Prevalence Of Malaria Parasitaemia In Pregnant Women Attending Antenatal Clinic At Jos University Teaching Hospital, Nigeria

EI Ikeh, SN Akudo, VE Uguru

 

Abstract

The prevalence of malaria parasitaemia in 200 pregnant women attending the antenatal clinic (ANC) of Jos University Teaching Hospital (JUTH) between April and June 2003 was determined. Geimsa-stained thick and thin blood films were examined microscopically for malaria parasites; the parasite densities were determined on the thick films. Eighteen (9%) of the women were positive for malaria parasites and only Plasmodium falciparum was encountered in the study. Pregnant women in the 15-20 year age group recorded the highest prevalence of 16%, closely followed by the age group 21-25 years with 15.2%. The 26-30, 31-35, 36-40 and 41-50 year age groups recorded 6.7%, 4.5%, 4.1% and 0% prevalence rates respectively. Women in their first trimester recorded 13.3% as against 10.2% and 3.8% for the second and third trimester respectively. The primigravidae had a prevalence of 12.9% as against 7.2% for multigravidae. Most of the women with malaria parasitaemia (89%) had parasite densities of less than 1000/µL of blood. The low prevalence of malaria parasitaemia in the ANC women is attributed to the regular prophylactic malaria therapy and the impacts of the health talks normally given to pregnant women during routine antenatal visits
Key words: Malaria, pregnancy, prevalence, prophylaxisAfr. J. Clin. Exper. Microbiol. 2005; 6(2): 91-94

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