[1]Obaro, H. K., 1Abdulkadir, B., and 2Abdullahi, S.
1Department of Microbiology, Umaru Musa Yar’adua University, Katsina, Katsina State, Nigeria
2Department of Pharmacology, Umaru Musa Yar’adua University, Katsina, Katsina State, Nigeria
*Correspondence to: obarohasan@yahoo.com; +2348136436916
Abstract:
Background: Neonatal sepsis is one of the most important causes of morbidity and mortality among neonates, particularly in developing countries. This study aimed to determine the risk factors and in vitro antibiotic susceptibility patterns of bacterial pathogens associated with neonatal sepsis in Federal Medical Centre (FMC) and Turai Umaru Yar’adua Maternal and Children Hospital (TUYMCH), Katsina, Nigeria.
Methodology: A total of 60 hospitalized neonates evaluated for neonatal sepsis at the special care baby units (SCBU) of the two healthcare facilities whose parents gave informed consent were enrolled for the study between July and December 2020. Blood samples were aseptically collected from the neonates and cultured on BacT/Alert automated platform (BioMérieux, Mercy-Etoile, France) machine. Bacteria were identified from all positive cultures and in vitro susceptibility test was performed on the isolates to determine their minimum inhibitory concentrations (MICs) to eight selected antibiotics using the Vitek-2 compact system. Data were analyzed by SPSS version 22.0. Continue reading “In vitro antibiotic susceptibility of bacterial pathogens and risk factors associated with culture positive neonatal sepsis in two hospitals, Katsina metropolis, Nigeria”