*1Shenge, J. A., 2Odaibo, G. N., and 2Olaleye, D. O.
1Virology Research Unit, Biological Sciences, Dominican University, Ibadan, Nigeria 2Department of Virology, College of Medicine, University of Ibadan, Nigeria *Correspondence to: jadamma@yahoo.com; +2348099711012
Abstract:
Background: Hepatitis C virus (HCV) genome undergoes high rate of mutation, which results in generation of genetically diverse HCV isolates. There is paucity of data on mutations in the nonstructural 5b (NS5b) gene of circulating HCV and their implications in the Nigerian population. Here, we identified clinically-important mutations in HCV isolates, which may influence response to therapy and disease prognosis. Continue reading “Predominant amino acid substitutions in NS5B gene of hepatitis C virus in blood donors and treatment-naïve hepatitis and HIV patients in Nigeria”