Comparative gender analysis of the seroprevalence of varicella zoster virus among HIV-infected individuals receiving care at Offa, north-central Nigeria

*1Udeze, A. O., and 2Odebisi-Omokanye, M.

1Virology Unit, Department of Microbiology, University of Ilorin, P.M.B 1515, Ilorin, Nigeria

2Infectious Disease, Environmental Health and Toxicity Research Group, Department of Microbiology, University of Ilorin, P.M.B 1515, Ilorin, Nigeria            *Correspondence to: udeze.ao@unilorin.edu.ng; austok90@yahoo.com; +2348135586003

ORCiD: 0000-0002-5492-4925

Abstract:

Background: Varicella zoster virus (VZV) infections are common and contribute substantially to morbidity and mortality among HIV-infected patients. This study was conducted to determine the level of exposure, compare the gender distribution pattern and correlate with CD4 count, history of chicken pox and demographics among HIV patients.

Methodology: Blood samples were collected from 273 randomly selected HIV-positive patients (93 males and 180 females) receiving care and management at the General Hospital Offa, Kwara State, Nigeria, between September 2019 and March 2020, after obtaining informed consent. Sera were separated from the blood samples and tested for the presence of VZV-specific IgG antibodies using Enzyme Linked Immunosorbent Assay (ELISA). Continue reading “Comparative gender analysis of the seroprevalence of varicella zoster virus among HIV-infected individuals receiving care at Offa, north-central Nigeria”