Leptospirosis: a need for increased awareness and improved laboratory testing

Clinical Laboratory Science Department, Winston-Salem State University, 304-D New Science Building, 601 S. Martin Luther King Jr. Drive, Winston-Salem, North Carolina 27110, USA Correspondence to: wishonl@wssu.edu; 336-750-8339 (work); 336-253-3677 (cell)

Abstract:
While leptospirosis is currently described as an emerging pathogen, there have likely been numerous cases worldwide each year for centuries. Hurricanes and other flooding events contribute to its spread through rodent urine, many cases of which go undiagnosed. This is especially problematic in developing countries where laboratory techniques may be out of date. There are over 100 cases per year in the United States of America, but millions of cases occur worldwide annually. Caused by many different species of fastidious, spiral-shaped Leptospira, it is difficult and slow to culture. Strides have been made to improve culture techniques in order to reduce the time to grow this genus of bacteria. Greater understanding of this disease by laboratorians, physicians, and other healthcare workers and improved laboratory identification techniques will help increase diagnoses and decrease morbidity and mortality of leptospirosis. Continue reading “Leptospirosis: a need for increased awareness and improved laboratory testing”

Re-emergence of monkeypox in Nigeria: a cause for concern and public enlightenment

A Fowotade, T.O. Fasuyi, R.A. Bakare

 

Abstract

Monkey pox infection is a zoonotic infection transmitted by direct or indirect contact with blood, body fluids and lesions of an infected animal. Human to human spread of Monkey pox has been described and infection is usually self-limiting, with an incubation period of 6-16 days. In Nigeria, the last case of monkey pox infection was recorded over 46 years ago. The recent emergence in Nigeria occurred in the year 2017 and was reported to have spread to 24 states with 228 suspected individuals affected. Laboratory diagnosis, as well as management and prevention of monkey pox infection in Nigeria, remain challenging as Nigeria is a resource-poor country with limited infrastructure, technical skill and training which is required in making a diagnosis. The ability of the monkey pox virus to evolve, its potential bioterrorism potential, as well as its recent emergence in Nigeria further justifies the need for improving the understanding of the presentation and prevention of monkey pox infection.

Keywords: monkey pox, emerging virus, Nigeria, rash, zoonosis, orthopox

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Re-emergence of monkeypox in Nigeria a cause for concern and public enlightenment