Category: Volume 5.3

A prospective study to determine the pattern of microorganisms seen in orofacial infections as well as investigating the antimicrobial susceptibility profile of the isolates was undertaken. Specimens were obtained aseptically from 25 patients presenting with orofacial infections at the Department of Oral Surgery and Pathology, Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, Nigeria. The specimens were transported in an anaerobically pre-reduced transport medium for processing in the laboratory. Isolation and identification were done employing standard bacteriological techniques. Antimicrobial susceptibility testing was performed by the disc diffusion method. All the 25 clinical samples obtained yielded growth of bacteria. Anaerobes were cultured from 24 (96%) specimens while 1 specimen yielded only aerobic isolates. Altogether, 44 bacterial isolates were obtained and 40 (91%) were anaerobes. Most of these anaerobes were Gram-negative rods and Gram-positive cocci. About 75-100% of the anaerobes were susceptible to commonly available antibiotics. Strikingly, sulphonamides demonstrated the weakest in-vitro activity against all isolates. The study revealed again the polymicrobial nature of orofacial infections as well as the predominance of anaerobes in the aetiology of these infections. Erythromycin and penicillin should be considered as frontline drugs in the treatment of mild orofacial infections while drugs like ciprofloxacin and clindamycin can be reserved for more severe and resistant infections.
Afr. J. Clin. Exper. Microbiol. 2004; 5 (3): 272-277

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Bacteriology And Antimicrobial Suceptibility Profile Of Agents Of Orofacial Infections In Nigerians

A survey of haemagglutination inhibition (HI) antibodies against influenza A virus was carried out on pigs sera collected at Bodija abattoir, Ibadan between December, 2001 and August 2002. Out of the 107 sera tested, 101 (94.39%) had HI antibodies to influenza A (H₁N₁) human strain while the remaining 6 (5.61%) were negative. The result of this work indicates that H₁N₁ influenza viruses are currently circulating among the pigs slaughtered in Bodija abattoir. The public health implications in terms of possible transmission contact with the pigs are discussed. The result of the HA titres obtained with turkey red blood cells (RBC) compared to that of guinea pig RBC indicated that the H₁N₁ stains of influenza A viruses have greater avidity for turkey RBC than those of guinea pigs. This is equally of diagnostic importance

Afr. J. Clin. Exper. Microbiol. 2004; 5 (3): 278-279

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Detection Of Haemagglutination–Inhibition Antibodies Against Human H1n1 Strains Of Influenza A Viruses In Swine In Ibadan, Nigeria

To determine if there was a bearing of body mass index (BMI) on male infertility, a cross-sectional study of males of infertile couples, attending our infertility clinic was carried out. Apart from BMI determination, the semens of these men were analyzed to ascertain their spermogram. Out of 47 men involved in the study, 66% (31) were below 40 years of age. Seventeen (36.2%) of these were between 30-39 years. About 49% of the study subjects had oligospermia, while 23.4% were azoospermic. Those subjects between 30-39 years had the worse spermogram. Thirty-two (68.1%) and 15(31.9%) of the whole population had good spermatozoa motility and morphology respectively. Poor BMI, whether low or elevated, affected the semen quality. In conclusion, infertile males should be encouraged to seek help early. Attending clinician should pay attention to their past or present genital infections and the biophysical parameters.

Afr. J. Clin. Exper. Microbiol. 2004; 5 (3): 280-284

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Seminal Fluid Analysis And Biophysical Profile Findings And Relevance In Infertile Males In Ilorin Nigeria