Prevalence and risk factors of acute gastroenteritis caused by Rotavirus among children in tertiary hospitals, southeastern Nigeria

*1Igwe, D., 2Oshun, P., 2Osuagwu, C., 1Efunshile, A., and 2Oduyebo, O.

1Department of Medical Microbiology, College of Medicine/Alex Ekwueme Federal University Teaching Hospital, Abakaliki, PMB 102, Ebonyi State, Nigeria
2College of Medicine/Lagos University Teaching Hospital, Idi-Araba, University of Lagos, Nigeria*Correspondence to: [email protected]

Abstract:
Background: Diarrhea is a worldwide problem and rotavirus is the commonest viral etiologic agent. In Nigeria, diarrhea causes more than 315,000 deaths of preschool-age children annually. In Ebonyi State, it is among the leading causes of pediatric emergency visits and one of the major causes of infant morbidity and mortality. This study was aimed at determining the prevalence and associated risk factors of acute gastroenteritis due to rotavirus infection among under-five children in Abakaliki, Ebonyi state.

This was a cross-sectional study of 275 children under 5 years of age hospitalized for acute watery diarrhea, who were consecutively recruited into the study. Stool samples were collected from each child for rotavirus antigen detection using an enzyme-linked immunosorbent assay (ELISA). Socio-demographic information of each child and selected risk factors were collected using structured questionnaire. Data analysis was done on SPSS software version 20.0, and association of demographic characteristics and risk factors with rotavirus diarrhoea was measured using Chi-square test, odds ratio (and 95% confidence interval). Significant value was set at p < 0.05. Continue reading “Prevalence and risk factors of acute gastroenteritis caused by Rotavirus among children in tertiary hospitals, southeastern Nigeria”

PROCEEDINGS OF THE 16TH ANNUAL GENERAL AND SCIENTIFIC MEETING OF THE COLLEGE OF NIGERIAN PATHOLOGISTS, PORT HARCOURT, RIVERS STATE, NIGERIA, 25TH – 26TH NOVEMBER, 2021

Ogbaini-Emovon, E.
Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, PMB 08, Edo State, Nigeria Correspondence to: [email protected]; +2348032424965

CONFERENCE ABSTRACTS/RÉSUMÉS DE LA CONFÉRENCE
Lassa virus persistence in body fluids after recovery from acute Lassa fever: a 2-year interim analysis of a prospective longitudinal cohort study

Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, PMB 08, Edo State, Nigeria Correspondence to: [email protected]; +2348032424965

Background: There is anecdotal evidence for Lassa virus persistence in body fluids. We investigated various body fluids after recovery from acute Lassa fever and describe the dynamics of Lassa virus RNA load in seminal fluid. The primary objective of this study was to quantitatively describe virus persistence and clearance and assess the infectivity of seminal fluid. Continue reading “PROCEEDINGS OF THE 16TH ANNUAL GENERAL AND SCIENTIFIC MEETING OF THE COLLEGE OF NIGERIAN PATHOLOGISTS, PORT HARCOURT, RIVERS STATE, NIGERIA, 25TH – 26TH NOVEMBER, 2021”