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Use of dexamethasone in the management of respiratory tract infections

*1Adegboro, B., 2Abayomi, S. A., 1Imran, J., and 3Sanni, E. O.

1Department of Medical Microbiology and Immunology, Nile University of Nigeria, Abuja, Nigeria

2Department of Medical Microbiology, LAUTECH Teaching Hospital, Ogbomoso, Nigeria

3Department of Haematology, Nile University of Nigeria, Abuja, Nigeria *Correspondence to: boazadegboro@gmail.com

Abstract:

Dexamethasone is a potent synthetic member of the glucocorticoid class of corticosteroid drugs that has been useful for the management of some pathological disorders because it affects a protean number of signaling pathways. It is used as adjunct therapy in the management of sepsis, arthritis, cardiac transplant, blood, hormone/immune system disorders, allergic reaction, skin, eye conditions, cancer and other pathologic disorders and as a mainstay of therapy in autoimmune hepatitis. With the advent of COVID-19, there have been investigations of its use as anti-inflammatory agent in severely ill patients. This present review elucidates the various studies on the use of dexamethasone in the management of severe respiratory tract infections, with the ultimate aim of reducing mortality amongst severely ill patients, including COVID-19. Continue reading “Use of dexamethasone in the management of respiratory tract infections”

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Demographic attributes of COVID-19 patients in an Infectious Disease Center of Nigeria

*1Arinola, G. O., 2Fashina, O. A., 3Oluyomi Ishola, O. C., 2Akinbola, O. I., 4Akinbile, S. A., 4Eegunjobi, A. O., 5Bello, M. D., 1Edem, F. V., 1Rahamon, S. K., 6Famuyiwa, O. I., 7Olaoti, A. J., 8Olaniyan, O. A., 5Oke, A. C., 10Fowotade, A., 11Abimbola, O., 5Johnson, J. O., 5Fagbemi, O. S., 9Salami, F., and 5,12Alonge, T. O.

1Department of Immunology, College of Medicine, University of Ibadan, Ibadan

2Department of Medical Microbiology, University College Hospital, lbadan

3National Blood Transfusion Service, Total Garden, Ibadan

4Central Diagnostic Centre, Total Garden, lbadan

5lnfectious Disease Centre, Olodo, lbadan

6Department of Chemical Pathology, University College Hospital, lbadan

7General Hospital, lgboho

8Department of Chemical Pathology, Ladoke Akintola University of Technology, Ogbomoso

9Oyo State Ministry of Health, Ibadan

10Department of Medical Microbiology, University of Ibadan

11Department of Medicine, University College Hospital, Ibadan

12Department of Surgery, College of Medicine, University of Ibadan, Ibadan

*Correspondence to: drarinolaog64@yahoo.com; +234 80-23451520; ORCID number: 0000-0001-7901-1498

Abstract:
Background: As part of our contribution to the growing pool of knowledge on the prevention and control of the COVID-19 pandemic, this study describes the demographic features of patients with COVID-19 hospitalized at Infectious Disease Center (IDC), Olodo, Ibadan, Oyo State, Nigeria. Continue reading “Demographic attributes of COVID-19 patients in an Infectious Disease Center of Nigeria”