*1,2Ade, T. I., 1Osiyemi, J. A., 2Aso, R. E., 3Akinduti, P. A., and 4Sunmola, N. O.
1Department of Medical Microbiology and Parasitology, University of Ilorin, Nigeria
2Department of Microbiology, Federal University Wukari, Taraba State, Nigeria
3Microbiology Unit, Department of Biological Sciences, Covenant University, Ota, Nigeria
4Department of Medical Microbiology and Parasitology, Olabisi Onabanjo University, Ogun State, Nigeria
*Correspondence to: tolulope.iorwuese@gmail.com; +2347066369670
Abstract:
Background: Inducible antibiotic resistance among Gram-positive cocci is a significant public health challenge that is grossly underreported within Africa, especially Nigeria. Hence, the aim of this study was to determine the prevalence of macrolide-lincosamide-streptogramin-B (MLSB) resistance among clinical isolates of Staphylococcus aureus at University of Ilorin Teaching Hospital, Ilorin, Nigeria.
Methodology: Clinical isolates were presumptively identified by Gram’s stain reaction and conventional biochemical tests such as catalase, coagulase, DNase, and mannitol fermentation. Phenotypic MLSB resistance was determined by placing clindamycin and erythromycin discs within 15 mm of each other and observing for a D-zone. Antibiotic sensitivity testing to selected antibiotics including cefoxitin for detection of methicillin resistance, was done using the modified Kirby-Bauer disc diffusion method. Continue reading “Prevalence of Macrolide-Lincosamide-Streptogramin-B resistance among clinical Staphylococcus aureus isolates in University of Ilorin Teaching Hospital, Ilorin, Nigeria”