Posted on

Prevalence of parasitic contamination of wastewater samples from selected slaughter houses in Benin City, Edo State, Nigeria

*Omoruyi, Z., and Omoaka, E. D.

Department of Medical Laboratory Science, School of Basic Medical Sciences, University of Benin, Benin City, Edo State, Nigeria

*Correspondence to: zainab.omoruyi@uniben.edu; Tel: +234 803 700 2791

Abstract:

Background: Wastewater from slaughterhouses can contain a variety of parasites, including protozoa and helminths. This study was designed to systematically examine wastewater samples from selected slaughter houses in Benin-City, Edo State, and determine the prevalence parasite contamination and spatial distribution of these parasites, to inform future public health and environmental protection strategies. Continue reading “Prevalence of parasitic contamination of wastewater samples from selected slaughter houses in Benin City, Edo State, Nigeria”

Posted on

Evaluation of α-fetoprotein and selected inflammatory enzyme markers in chronic hepatitis B patients seropositive and seronegative for hepatitis B envelope antibody in UITH, Ilorin, Nigeria

1Nma, M. A., 2Yaqub, S. A., and *2Olufemi, O. J.

1Faculty of Health Sciences, Al-Hikmah University, Ilorin, Kwara State, Nigeria

2Department of Immunology, College of Medicine, University of Ibadan, Nigeria

*Correspondence to: olayinkajoshua1@gmail.com

 

Abstract:

 Background: Hepatitis B virus (HBV) can cause both acute and chronic hepatitis and is a leading contributor to hepatic cirrhosis and hepatocellular carcinoma (HCC), imposing a substantial burden on healthcare systems due to its high morbidity, mortality, and treatment costs. HBV infection remains a major public health concern, particularly in sub-Saharan Africa. Investigating the serum levels of alpha-fetoprotein (AFP) and selected inflammatory markers in individuals seropositive for hepatitis B envelope antibody (HBeAb) provides valuable insights into disease progression, early detection of HCC, and monitoring treatment efficacy. This study assessed serum levels of AFP and selected inflammatory markers such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), total protein, albumin, and globulin among chronic HBV patients seropositive and seronegative for HBeAb at the University of Ilorin Teaching Hospital (UITH), Ilorin, Nigeria. Continue reading “Evaluation of α-fetoprotein and selected inflammatory enzyme markers in chronic hepatitis B patients seropositive and seronegative for hepatitis B envelope antibody in UITH, Ilorin, Nigeria”

Posted on

Bloodstream infection caused by Kocuria species in a tertiary hospital in Lagos, Nigeria: A case series

*1Osuagwu, C. S., 2,3Davies, A. A., and 1Oladele R. O.

1Department of Medical Microbiology and Parasitology, Lagos University Teaching Hospital, Idi-Araba, Lagos, Nigeria

 2Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, Idi-Araba, Lagos, Nigeria

3Department of Medical Microbiology and Parasitology, Olabisi University Teaching Hospital, Sagamu, Nigeria

*Correspondence to: chiomaosuagwu@gmail.com

Abstract

Kocuria species are emerging opportunistic pathogens commonly misidentified as coagulase-negative staphylo- coccus. Improvement in laboratory diagnostic techniques and the expansion in the number of patients with immunocompromised diseases has led to the rising number of Kocuria infections being reported. We report cases of Kocuria bacteraemia in three immunocompromised patients. The first case was an 11-year-old with metastatic nasopharyngeal carcinoma and Kocuria kristinae isolated from the second blood culture, but due to discharge of the patient against medical advice, the role of K. kristinae and outcome of the case could not be ascertained. The second case was a 30-year-old with acute lymphoblastic leukaemia, with fever and diarrhoea, and Kocuria species isolated from the second blood culture, but despite treatment with antibiotic with invitro activity against the organism, the outcome was fatal. The third case was a very low birth weight premature male neonate who was delivered by emergency cesarean at 31 weeks gestation, due to maternal chronic hypertension and superimposed preeclampsia. Although, Kocuria rosea was isolated from the third blood culture of the case, it was most likely a colonizer, as the clinical condition of the patient had improved before isolating the organism. This report may be the first case of bacteraemia caused by Kocuria from Nigeria, indicating that this organism should not ignored as a possible cause of bacteraemia because advancement in laboratory diagnostics will aid correct identification. Continue reading “Bloodstream infection caused by Kocuria species in a tertiary hospital in Lagos, Nigeria: A case series”

Posted on

Antibiotic susceptibility of bacteria isolated from suppurative acute otitis media in children in Ouagadougou, Burkina Faso  

[1],3Tondé, I., [2]Guiguemdé, K. T., *[3],[4]Condé, M. S., 2Savadogo, P. M., 2,3Sanogo, Z., 1,3Tapsoba, A., 3Tamboura, M., 2,3Soma, W., 1Béré, P. L., 3Somé, C. K., 1Ky/Ba, A., 1Sanou, I., and [5]Gyebré, Y. M. C.

1Laboratory of Bacteriology-Virology, UFR SDS, Joseph Ki-Zerbo Université, Ouagadougou, Burkina Faso

2Laboratory of Parasitology-Mycology, UFR SDS, Joseph Ki-Zerbo Université, Ouagadougou, Burkina Faso

3Department of Biomedical Analysis Laboratory, Charles de Gaulle Pediatric University Hospital, Ouagadougou, Burkina Faso

4Department of Biomedical Analysis Laboratory, Ignace Deen University Hospital, Conakry Guinea

5Department of Otolaryngology, Yalgado Ouédraogo University Hospital, Ouagadougou, Burkina Faso *Correspondence to: mamadisaran93@gmail.com; Tel: (226) 64645543

Abstract:

Background: Acute otitis media (AOM) is one of the most common bacterial infections in children. The emergence of antimicrobial resistance (AMR) poses a threat to the management of these infections. The objective of this study was to identify and describe the sensitivity profile of bacterial agents isolated in AOM to commonly used antibiotics in the city of Ouagadougou, Burkina Faso.                            Continue reading “Antibiotic susceptibility of bacteria isolated from suppurative acute otitis media in children in Ouagadougou, Burkina Faso  “

Posted on

Evaluation of microbial quality of grilled foods sold at roadside in Calabar metropolis, Cross River State, Nigeria

*1Inyang, A. N., 2Agiang, M. A., 2Mgbang, J. E., 2Arikpo, O. O., 2Ottoho, E. O., and 2Eze, D. E.

1Department of Biochemistry, Arthur Jarvis University, Akpabuyo, Nigeria

2Department of Biochemistry, University of Calabar, Calabar, Nigeria

*Correspondence to: aniekemeinyang39@gmail.com; Mobile: +234(0)813 566 8258

Abstract:

Background: Roadside foods are central parts of culinary custom in many African countries. In addition to their dietary importance, they contribute immensely to the national and economic values of a nation. However, the growing incidence of food-borne illnesses in relation to the roadside foods is a great concern. Hence, this study assessed the microbial quality of grilled foods sold at roadside in Calabar metropolis, Cross River State, Nigeria.      Continue reading “Evaluation of microbial quality of grilled foods sold at roadside in Calabar metropolis, Cross River State, Nigeria”

Posted on

Prevalence and antibiotic susceptibility of acute bacterial meningitis isolates among children with fever and convulsion in Federal Medical Centre, Bida, Nigeria

[1]Oyeleye, A. E., 1Afeez, B. O., 1Ayanbeku, T. S., and *2Ubesie, A. C.

 1Department of Paediatrics, Federal Medical Centre, Bida, Niger State, Nigeria   2Department of Paediatrics, College of Medicine, University of Nigeria, Enugu State, Nigeria

*Correspondence to: agozie.ubesie@unn.edu.ng

Abstract:

Background: Acute bacterial meningitis (ABM) is a life-threatening illness associated with high morbidity and mortality as well as debilitating consequences among survivors. The objective of this study is to determine the prevalence of bacterial isolates and antibiotic susceptibility pattern of ABM among children presenting with fever and convulsion at the Federal Medical Centre, Bida, Nigeria.         Continue reading “Prevalence and antibiotic susceptibility of acute bacterial meningitis isolates among children with fever and convulsion in Federal Medical Centre, Bida, Nigeria”

Posted on

Molecular epidemiology of genital Chlamydia trachomatis infections among women of reproductive age living with HIV/AIDS in a Nigerian tertiary health institution

*1,2,3Abayomi, S. A., 3Akanbi, A. A., 2Taiwo, S. S., 4Omoare, A. A., and 5Adegboro, B.

 1Cancer Research UK, Swansea, Wales, United Kingdom                                                2Department of Medical Microbiology and Parasitology, LAUTECH Teaching Hospital, Ogbomoso, Nigeria

3Department of Medical Microbiology and Parasitology, University of Ilorin Teaching Hospital, Ilorin, Nigeria

4Public Health Laboratory Services, Nigeria Centre for Disease Control and Prevention (NCDC), Abuja, Nigeria

5Department of Medical Microbiology and Immunology, Nile University of Nigeria, Abuja, Nigeria  *Correspondence to: subslaabayomi@gmail.com

Abstract:

Background: Chlamydia trachomatis is the most prevalent bacterial pathogen causing sexually transmitted infections (STIs) globally. This study investigates the genovars of genital C. trachomatis infection among women of reproductive age living with HIV/AIDS in Ilorin, Nigeria.      Continue reading “Molecular epidemiology of genital Chlamydia trachomatis infections among women of reproductive age living with HIV/AIDS in a Nigerian tertiary health institution”

Posted on

Antibiotic resistance profile of Non-Fermenting Gramnegative bacteria recovered from clinical specimens in a tertiary care teaching hospital, Hyderabad, India

*Kumuda, A., and Pavani, G.

Department of Microbiology, Apollo Institute of Medical Sciences and Research, Hyderabad, India *Correspondence to: kumudarumugam@gmail.com; +918805647838

 Abstract

 Background: Non-Fermenting Gram-negative bacilli (NFGNB), including Pseudomonas aeruginosa, Acinetobacter species, and Burkholderia species, are emerging as significant opportunistic pathogens, especially in immunocompromised and hospitalized patients. These organisms pose a major therapeutic challenge due to their multidrug-resistance (MDR) and intrinsic resistance mechanisms. The goal of this study is to determine antibiotic susceptibility pattern of NFGNB isolated from clinical specimens of patients in a tertiary care teaching hospital in Hyderabad, India.

Methodology: A descriptive cross-sectional observational study of patients with clinical infections was conducted between December 2024 and April 2025, to identify NFGNB from their clinical specimens. Different clinical samples (blood, sputum, urine, pus and others) were collected from patients of both sexes and all age groups for bacterial isolation using automated Bact/Alert for blood culture and conventional method for other samples. Identification of NFGNB isolates and antimicrobial susceptibility testing (AST) of the isolates against selected antibiotics were performed using the VITEK 2 Compact system, and AST interpretations were made in line with the Clinical and Laboratory Standards Institute (CLSI) guidelines. Continue reading “Antibiotic resistance profile of Non-Fermenting Gramnegative bacteria recovered from clinical specimens in a tertiary care teaching hospital, Hyderabad, India”

Posted on

Phenotypic identification and species characterization of clinically significant coagulase-negative staphylococci isolates at Bouaké University Hospital, Côte d’Ivoire

*1,2N’Guessan, A. M., 1,2Monemo, P., 1Traoré, A., 1,2Tadet, J. O. N., 1,2Gawa, K. J.,

1Ouattara, A., and 1,2Akoua Koffi, C.

1Bacteriology-Virology Laboratory, Bouaké University Hospital Center, Ivory Coast      r2Faculty of Medical Sciences, Alassane Ouattara University, Ivory Coast

*Correspondence to: mienmooh@gmail.com; +2250707669820

 

Abstract:

 Background: Coagulase-negative staphylococci (CoNS) are now recognized as important agents of nosocomial infections, particularly in immunocompromised patients in the healthcare settings, due to their ability to form biofilms and their high resistance to methicillin. The aim of this study is to identify and characterize different species of CoNS isolated at the Bacteriology-Virology Laboratory of the Bouaké University Hospital, Côte d’Ivoire Continue reading “Phenotypic identification and species characterization of clinically significant coagulase-negative staphylococci isolates at Bouaké University Hospital, Côte d’Ivoire”