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Prevalence and antibiotic susceptibility of acute bacterial meningitis isolates among children with fever and convulsion in Federal Medical Centre, Bida, Nigeria
[1]Oyeleye, A. E., 1Afeez, B. O., 1Ayanbeku, T. S., and *2Ubesie, A. C.
1Department of Paediatrics, Federal Medical Centre, Bida, Niger State, Nigeria 2Department of Paediatrics, College of Medicine, University of Nigeria, Enugu State, Nigeria
*Correspondence to: agozie.ubesie@unn.edu.ng
Abstract:
Background: Acute bacterial meningitis (ABM) is a life-threatening illness associated with high morbidity and mortality as well as debilitating consequences among survivors. The objective of this study is to determine the prevalence of bacterial isolates and antibiotic susceptibility pattern of ABM among children presenting with fever and convulsion at the Federal Medical Centre, Bida, Nigeria. Continue reading “Prevalence and antibiotic susceptibility of acute bacterial meningitis isolates among children with fever and convulsion in Federal Medical Centre, Bida, Nigeria”
Molecular epidemiology of genital Chlamydia trachomatis infections among women of reproductive age living with HIV/AIDS in a Nigerian tertiary health institution
*1,2,3Abayomi, S. A., 3Akanbi, A. A., 2Taiwo, S. S., 4Omoare, A. A., and 5Adegboro, B.
1Cancer Research UK, Swansea, Wales, United Kingdom 2Department of Medical Microbiology and Parasitology, LAUTECH Teaching Hospital, Ogbomoso, Nigeria
3Department of Medical Microbiology and Parasitology, University of Ilorin Teaching Hospital, Ilorin, Nigeria
4Public Health Laboratory Services, Nigeria Centre for Disease Control and Prevention (NCDC), Abuja, Nigeria
5Department of Medical Microbiology and Immunology, Nile University of Nigeria, Abuja, Nigeria *Correspondence to: subslaabayomi@gmail.com
Abstract:
Background: Chlamydia trachomatis is the most prevalent bacterial pathogen causing sexually transmitted infections (STIs) globally. This study investigates the genovars of genital C. trachomatis infection among women of reproductive age living with HIV/AIDS in Ilorin, Nigeria. Continue reading “Molecular epidemiology of genital Chlamydia trachomatis infections among women of reproductive age living with HIV/AIDS in a Nigerian tertiary health institution”
Antibiotic resistance profile of Non-Fermenting Gramnegative bacteria recovered from clinical specimens in a tertiary care teaching hospital, Hyderabad, India
*Kumuda, A., and Pavani, G.
Department of Microbiology, Apollo Institute of Medical Sciences and Research, Hyderabad, India *Correspondence to: kumudarumugam@gmail.com; +918805647838
Abstract
Background: Non-Fermenting Gram-negative bacilli (NFGNB), including Pseudomonas aeruginosa, Acinetobacter species, and Burkholderia species, are emerging as significant opportunistic pathogens, especially in immunocompromised and hospitalized patients. These organisms pose a major therapeutic challenge due to their multidrug-resistance (MDR) and intrinsic resistance mechanisms. The goal of this study is to determine antibiotic susceptibility pattern of NFGNB isolated from clinical specimens of patients in a tertiary care teaching hospital in Hyderabad, India.
Methodology: A descriptive cross-sectional observational study of patients with clinical infections was conducted between December 2024 and April 2025, to identify NFGNB from their clinical specimens. Different clinical samples (blood, sputum, urine, pus and others) were collected from patients of both sexes and all age groups for bacterial isolation using automated Bact/Alert for blood culture and conventional method for other samples. Identification of NFGNB isolates and antimicrobial susceptibility testing (AST) of the isolates against selected antibiotics were performed using the VITEK 2 Compact system, and AST interpretations were made in line with the Clinical and Laboratory Standards Institute (CLSI) guidelines. Continue reading “Antibiotic resistance profile of Non-Fermenting Gramnegative bacteria recovered from clinical specimens in a tertiary care teaching hospital, Hyderabad, India”
Phenotypic identification and species characterization of clinically significant coagulase-negative staphylococci isolates at Bouaké University Hospital, Côte d’Ivoire
*1,2N’Guessan, A. M., 1,2Monemo, P., 1Traoré, A., 1,2Tadet, J. O. N., 1,2Gawa, K. J.,
1Ouattara, A., and 1,2Akoua Koffi, C.
1Bacteriology-Virology Laboratory, Bouaké University Hospital Center, Ivory Coast r2Faculty of Medical Sciences, Alassane Ouattara University, Ivory Coast
*Correspondence to: mienmooh@gmail.com; +2250707669820
Abstract:
Background: Coagulase-negative staphylococci (CoNS) are now recognized as important agents of nosocomial infections, particularly in immunocompromised patients in the healthcare settings, due to their ability to form biofilms and their high resistance to methicillin. The aim of this study is to identify and characterize different species of CoNS isolated at the Bacteriology-Virology Laboratory of the Bouaké University Hospital, Côte d’Ivoire Continue reading “Phenotypic identification and species characterization of clinically significant coagulase-negative staphylococci isolates at Bouaké University Hospital, Côte d’Ivoire”
Comparative evaluation of GenoType MTBDRplus line probe assay and solid culture for detection of drug-resistant tuberculosis in northcentral Nigeria
*1,[1]Eliya, T. T., 1,2Ajide, B. A., 1Bassey, E., 1,2Ishaku, P., 1,5Adeyanju, B. D., 1Jonathan, K, and 1,[2],[3]John, B.
1Zankli Research Centre, Bingham University Karu, Km 26 Abuja-Keffi Expressway, Karu, Nigeria
2Biological Sciences Department, Bingham University Karu, Km 26 Abuja-Keffi Expressway, Karu, Nigeria
3Clinical Sciences, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom
4Community Medicine, Bingham University Karu, Km 26 Abuja-Keffi Expressway, Karu, Nigeria
[4]Institute of Human Virology, Plot 62 Emeritus Zone, Abuja, Nigeria
*Correspondence to: iliya.taryuta@binghamuni.edu.ng; +2347034229746
Abstract:
Background: Multi-drug resistant tuberculosis (MDR-TB) poses a great threat to the TB control programs worldwide. Early detection of rifampicin (RIF) and isoniazid (INH)-resistant Mycobacterium tuberculosis (MTB) is essential for effective treatment and control of MDR-TB. This study evaluated the performance of GenoType MTBDRplus Line Probe Assay (LPA) with the solid culture method for early diagnosis of MDR-TB. Continue reading “Comparative evaluation of GenoType MTBDRplus line probe assay and solid culture for detection of drug-resistant tuberculosis in northcentral Nigeria”
Prevalence and predictors of hepatitis B screening among pregnant women attending antenatal clinics in three primary health centres in Abeokuta, Nigeria: A cross-sectional study
*Aliu, O. O., Fowotade, A., and Omoruyi, C. E.
Department of Medical Microbiology, University College Hospital (UCH), Ibadan, Nigeria
*Correspondence to: aliu_my2004@yahoo.com
Abstract:
Background: Hepatitis B virus (HBV) infection remains a major public‑health concern. Antenatal screening identifies maternal infection and enables interventions to prevent mother‑to‑child transmission. We assessed the prevalence and predictors of prior HBV screening among pregnant women attending three primary health centres in southwest Nigeria.
Methodology: This was a cross‑sectional survey of 289 pregnant women consecutively enrolled at the antenatal clinics of the three selected health centres. A standardized questionnaire was interviewer-administered to each participant to collect information on socio‑demographic characteristics, previous HBV screening and behavioral and healthcare‑ factors related to HBV screening. Data were analysed using SPSS. Associations of factors with prior HBV screening were determined using Chi‑square and multivariable logistic regression estimated adjusted Odd ratio (AOR) with 95% confidence interval (CI). Continue reading “Prevalence and predictors of hepatitis B screening among pregnant women attending antenatal clinics in three primary health centres in Abeokuta, Nigeria: A cross-sectional study”
Knowledge, perception and uptake of human papillomavirus (HPV) vaccine among future healthcare providers: Insights from a medical school in Ogun State, Nigeria
*[1]Akinola-Fowotade, O., [2]Oluwole, T. O., 3Omobowale, O., and 4Fowotade, A.
1Benjamin S. Carson College of Health and Medical Sciences, Babcock University, Ogun State, Nigeria
2Department of Medical Microbiology, Babcock University, Ogun State, Nigeria
3Department of Community Medicine, College of Medicine, University of Ibadan, Nigeria
4Department of Medical Microbiology and Parasitology, College of Medicine, University of Ibadan, Nigeria *Correspondence to: onaopemipofowotade@gmail.com; +2348108671326
Abstract:
Background: Human papillomavirus (HPV) is the primary cause of cervical cancer. Despite the availability of highly effective vaccines, awareness and uptake remain inadequate in many low- and- middle-income countries. Medical students, as future healthcare providers, play a crucial role in patient education, health promotion, and vaccine advocacy within their communities. Their knowledge, attitudes, and personal vaccination behaviors directly influence their ability to counsel patients and recommend HPV vaccination effectively. Understanding the knowledge levels, perceptions, and barriers to HPV vaccination among this population is essential for developing targeted educational interventions. The objective of this study is to assess the knowledge, perception, and uptake of HPV vaccination among female medical students in a tertiary institution in Nigeria. Continue reading “Knowledge, perception and uptake of human papillomavirus (HPV) vaccine among future healthcare providers: Insights from a medical school in Ogun State, Nigeria”
Aetiologic agents of cutaneous mycoses at the parasitologymycology laboratory of University Center Hospital Joseph Ravoahangy Andrianavalona (CHU JRA), Antananarivo, Madagascar
*1,2Zafindraibe, N. J., 2Andriambao, H. M. R., 2Rasamindrakotroka, A., and 2Razanakolona, L. R. S.
1Bacteriology, Parasitology-Mycology Laboratory, University Center Hospital Joseph Ravoahangy Andrianavalona (CHU JRA), Antananarivo, Madagascar
2Department of Biology, Faculty of Medicine, Antananarivo University, Madagascar
*Correspondence to: juliemail_21@yahoo.fr; njzafindraibe@gmail.com
Abstract:
Background: Superficial and cutaneous fungal infections are among the most common dermatological conditions worldwide, particularly in tropical and subtropical regions. Caused by a variety of fungi (yeasts, dermatophytes, and molds), they can result in significant morbidity. In resource-limited settings such as Madagascar, their true burden remains underestimated due to limited access to diagnostic facilities and frequent empirical treatment. Local epidemiological data are essential for improving diagnosis and management strategies. The objectives of this study are to determine the prevalence, species distribution, affected anatomical sites and demographic characteristics of patients with superficial and cutaneous mycoses diagnosed at the University Center Hospital Joseph Ravoahangy Andrianavalona (CHU JRA) in Antananarivo, Madagascar. Continue reading “Aetiologic agents of cutaneous mycoses at the parasitologymycology laboratory of University Center Hospital Joseph Ravoahangy Andrianavalona (CHU JRA), Antananarivo, Madagascar”
Antifungal resistance pattern of Candida species isolated from clinical specimens of patients in selected healthcare facilities in Yenagoa, Nigeria
[1]Baraikio, D., [2]Daokoru-Olukole, C., and 3Abdu, A. B.
1Department of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmacy, Niger Delta University, Wilberforce-Island, Bayelsa State, Nigeria
2Department of Microbiology, Faculty of Science, Niger Delta University, Wilberforce-Island, Bayelsa State, Nigeria
3Department of Medical Microbiology and Parasitology, Faculty of Basic Clinical Sciences, Niger Delta University, Wilberforce-Island, Bayelsa State, Nigeria
*Correspondence to: simply4didi@yahoo.com; +2348035391089 Abstract:
Background: Candida species are normal flora of humans that can be pathogenic and cause candidiasis. Candidiasis is a public health problem due to its high prevalence, mortality, and increased costs of care associated with serious systemic Candida infections. This study was designed to identify the antifungal resistance pattern of Candida species isolated from different clinical specimens in Yenagoa, Bayelsa State, Nigeria, and to detect resistant genes associated with the Candida species. Continue reading “Antifungal resistance pattern of Candida species isolated from clinical specimens of patients in selected healthcare facilities in Yenagoa, Nigeria”