1Nma, M. A., 2Yaqub, S. A., and *2Olufemi, O. J.
1Faculty of Health Sciences, Al-Hikmah University, Ilorin, Kwara State, Nigeria
2Department of Immunology, College of Medicine, University of Ibadan, Nigeria
*Correspondence to: olayinkajoshua1@gmail.com
Abstract:
Background: Hepatitis B virus (HBV) can cause both acute and chronic hepatitis and is a leading contributor to hepatic cirrhosis and hepatocellular carcinoma (HCC), imposing a substantial burden on healthcare systems due to its high morbidity, mortality, and treatment costs. HBV infection remains a major public health concern, particularly in sub-Saharan Africa. Investigating the serum levels of alpha-fetoprotein (AFP) and selected inflammatory markers in individuals seropositive for hepatitis B envelope antibody (HBeAb) provides valuable insights into disease progression, early detection of HCC, and monitoring treatment efficacy. This study assessed serum levels of AFP and selected inflammatory markers such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), total protein, albumin, and globulin among chronic HBV patients seropositive and seronegative for HBeAb at the University of Ilorin Teaching Hospital (UITH), Ilorin, Nigeria. Continue reading “Evaluation of α-fetoprotein and selected inflammatory enzyme markers in chronic hepatitis B patients seropositive and seronegative for hepatitis B envelope antibody in UITH, Ilorin, Nigeria”