*1,2Boni, C., 1Kouakou, C., 2Gnegouri, R., 2Benié Ackah, J., and 1Koffi, K. S.
1Department of Fundamental and Biological Sciences, Faculty of Medical Sciences, Félix Houphouët-Boigny University, Abidjan, Côte d’Ivoire
2Laboratory Department, Alassane Ouattara National Center of Oncology and Radiotherapy (CNRAO), Abidjan, Côte d’Ivoire
*Correspondence to: boni.cho@ufhb.edu.ci; +2250505083523
Abstract:
Background: Febrile episodes in patients undergoing chemotherapy pose a major risk for bloodstream infections (BSIs). Prompt microbiological diagnosis is essential to guide targeted therapy and minimize the emergence of antimicrobial resistance.
Methodology: A six-month cross-sectional study (July–December 2024) was conducted at the Alassane Ouattara National Center of Oncology and Radiotherapy (CNRAO), Abidjan, Côte d’Ivoire. All chemotherapy patients presenting with fever (≥38.5°C) were included. Blood cultures were processed using the BACT/ALERT system, and bacterial identification with antimicrobial susceptibility testing followed CA-SFM 2022 guidelines. ESBL and carbapenemase production in Gram-negative isolates was detected in line with CA-SFM/EUCAST guidelines while methicillin resistance (MR), macrolide-lincosamide-streptogramin B (MLSB), and kanamycin-tobramycin-genta- micin (KTG) resistance phenotypes in Gram-positive isolates were detected in line with CLSI/CA-SFM standard. Continue reading “Microbiological profile of bacteraemia in febrile patients receiving chemotherapy: Experience of the Alassane Ouattara National Center of Oncology and Radiotherapy (CNRAO), 2024”