Bacterial contaminants

*^[1]Famojuro, O. B., ^[2]Famojuro, T. I., ³Adewusi, O. M., and ⁴Oluwatobi, O. B.

¹Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Olabisi Onabanjo University, Ogun State, Nigeria

²Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Bingham University, Karu, Nasarawa State, Nigeria

³Seal Healthcare Limited, Ipaja, Lagos State, Nigeria

⁴Department of Medical Laboratory Science, University of Ibadan, Ibadan, Oyo state, Nigeria

*Correspondence to: olaniran.oluwatoyin@oouagoiwoye.edu.ng; +2349062214760

Abstract:

Background: The increasing usage of mobile phones in healthcare settings is cause for concern because these gadgets could be used to disseminate harmful bacteria. This study aimed to detect the presence of bacterial pathogens and carriage of metallo-β-lactamase (MBL) genes in Gram-negative bacteria from mobile phones of healthcare workers (HCWs) and medical students at the Olabisi Onabanjo University Teaching Hospital, Ogun State, Nigeria. Continue reading “Prevalence of bacterial pathogens and molecular detection of metallo-β-lactamases in Gram-negative bacteria from mobile phones of healthcare workers in a Nigerian tertiary hospital”

*Udeogu, C. V., Agbakoba, N. R., and Chukwuma, G. O.
Medical Microbiology Unit, Department of Medical Laboratory Science
Nnamdi Azikiwe University, Nnewi, Anambra State, Nigeria Correspondence to: chidozie.udeogu@yahoo.com

Abstract:

Background: The use of herbal medicine continues to remain popular despite advances in orthodox medicine largely as a result of affordability and availability. However, contaminated and potentially toxic polyherbal preparations remain a public health challenge despite regulations instituted by concerned agencies in Nigeria. The objective of this study was to determine and compare the bacterial contaminants of different polyherbal products sold in Nnewi, Nigeria

Methodology: This study evaluated the bacteriological profile of 22 packaged and 22 unpackaged polyherbal preparations sold in Nnewi, Nigeria. The samples were collected from different herbal medicine shops in Nnewi by simple random sampling and were assayed for comparative bacterial loads with chromogenic media and their total viable counts evaluated following standard method for microbial load analysis.

Results: Bacterial contaminants were isolated from 9 of 22 (40.9%) packaged polyherbal samples while 13 of 22 (59.1%) samples were bacteriologically sterile. For the unpackaged polyherbal, bacterial contaminants were isolated from 18 of 22 (81.8%) samples while 4 of 22 (18.2%) were bacteriologically sterile (OR 0.1538, p=0.0122). The most frequently isolated bacterial contaminant in the packaged polyherbal samples was Enterococcus faecalis with 33.3% (6/18) while Salmonella sp was the least frequently isolated with 5.6% (1/18). For the unpackaged polyherbals, the most frequently isolated bacterial contaminant was Staphylococcus aureus with 25% (7/28) while Salmonella sp and E. faecalis were the least frequently isolated with 10.7% (3/28) each. The median total viable count of the packaged group of the polyherbal products was 1.48×106 CFU/ml, while the median total viable count for unpackaged group of polyherbals was 1.95×106 CFU/ml.

Conclusion: This study shows that many polyherbal products sold in Nnewi are potentially contaminated with bacterial agents. It is therefore imperative that herbal medicine practitioners be enlightened on hygienic ways of preventing microbial contamination during polyherbal production.

Keywords: Bacterial contaminants, herbal products, Nnewi, Nigeria Continue reading “Comparative distribution of bacterial contaminants of packaged and unpackaged polyherbal products sold in Nnewi, Nigeria”