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Bloodstream infection caused by Kocuria species in a tertiary hospital in Lagos, Nigeria: A case series

*1Osuagwu, C. S., 2,3Davies, A. A., and 1Oladele R. O.

1Department of Medical Microbiology and Parasitology, Lagos University Teaching Hospital, Idi-Araba, Lagos, Nigeria

 2Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, Idi-Araba, Lagos, Nigeria

3Department of Medical Microbiology and Parasitology, Olabisi University Teaching Hospital, Sagamu, Nigeria

*Correspondence to: chiomaosuagwu@gmail.com

Abstract

Kocuria species are emerging opportunistic pathogens commonly misidentified as coagulase-negative staphylo- coccus. Improvement in laboratory diagnostic techniques and the expansion in the number of patients with immunocompromised diseases has led to the rising number of Kocuria infections being reported. We report cases of Kocuria bacteraemia in three immunocompromised patients. The first case was an 11-year-old with metastatic nasopharyngeal carcinoma and Kocuria kristinae isolated from the second blood culture, but due to discharge of the patient against medical advice, the role of K. kristinae and outcome of the case could not be ascertained. The second case was a 30-year-old with acute lymphoblastic leukaemia, with fever and diarrhoea, and Kocuria species isolated from the second blood culture, but despite treatment with antibiotic with invitro activity against the organism, the outcome was fatal. The third case was a very low birth weight premature male neonate who was delivered by emergency cesarean at 31 weeks gestation, due to maternal chronic hypertension and superimposed preeclampsia. Although, Kocuria rosea was isolated from the third blood culture of the case, it was most likely a colonizer, as the clinical condition of the patient had improved before isolating the organism. This report may be the first case of bacteraemia caused by Kocuria from Nigeria, indicating that this organism should not ignored as a possible cause of bacteraemia because advancement in laboratory diagnostics will aid correct identification. Continue reading “Bloodstream infection caused by Kocuria species in a tertiary hospital in Lagos, Nigeria: A case series”

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Automated blood culture systems for isolation of bacterial pathogens of bloodstream infection: The experience of Bobo-Dioulasso Teaching Hospital, Burkina Faso

1Nagalo, A., 1Kaboré, O. D., 1Koulbou, M., 2Sanogo, B., 3Yehouenou, C. L., 5Traoré, I., 4Zoungrana, J., 4Poda, A., and 1Ouédraogo, A-S.

 1Department of Bacteriology Laboratory, Sourô Sanou University Hospital, 01 BP 676, Bobo-Dioulasso, Burkina Faso

2Department of Medical Paediatrics, Sourô Sanou University Hospital, 01 BP 676, Bobo-Dioulasso, Burkina Faso

3Mycobacteria Reference Laboratory (LRM), BP 817, Cotonou, and Faculty of Health Sciences, University of Abomey Calavi, Cotonou, Bénin

4Department of Infectious Diseases, Sourô Sanou University Hospital, 01 BP 676, Bobo-Dioulasso, Burkina Faso

5Department of Intensive Cares, Sourô Sanou University Hospital, 01 BP 676, Bobo-Dioulasso, Burkina Faso

*Correspondence to: nagaloandre@gmail.com; +226 71407137

 

Abstract:

Background: Identification of the causative agent is an essential requirement for better treatment of bloodstream infection. The BacT/Alert 3D (BioMérieux, Marcy l’Étoile, France), is a blood culture system equipped with CO2 sensors to monitor the growth of microorganisms in blood culture bottles designed to optimize bacterial growth. The aim of this study was to determine the performance of this equipment in detecting bacterial pathogens from patients with bloodstream infection in the context of low-and-middle-income countries (LMICs), with Bobo-Dioulasso Teaching Hospital as a case study. Continue reading “Automated blood culture systems for isolation of bacterial pathogens of bloodstream infection: The experience of Bobo-Dioulasso Teaching Hospital, Burkina Faso”