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Prevalence and distribution of the World Health Organization-Bacterial Priority Pathogens in selected hospitals in Katsina State, Nigeria

*1,2Suleiman, H. A., 1Mukhtar, G. L., and 1Hayatuddeen, M. R.

1Department of Microbiology, Faculty of Natural and Applied Science, Umaru Musa Yar’adua University, Katsina, Nigeria

2Department of Medicine, General Hospital Kankia, Katsina State, Nigeria          *Correspondence to: suleimanaliyuhayatulah@gmail.com; Tel: 08030835316; ORCID: 0009-0007-9878-3582

Abstract: 

Background: Infections caused by antibiotic-resistant bacteria have become a major global public health challenge, as they can reduce the effectiveness of modern medical treatments and clinical care. The most important of these pathogens are those listed in the World Health Organization (WHO) Bacterial Priority Pathogens List (BPPL) of 2024. This study determined the prevalence, distribution, and antimicrobial resistance patterns of the WHO bacterial priority pathogens in three selected hospital settings in Katsina State, Nigeria. Continue reading “Prevalence and distribution of the World Health Organization-Bacterial Priority Pathogens in selected hospitals in Katsina State, Nigeria”

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Comparative analysis of biofilm formation in carbapenem-resistant and carbapenem-susceptible Klebsiella pneumoniae clinical isolates from a tertiary hospital in Nigeria

*¹Otaru, B. M., 2Aikhomu V., and ¹Oladele, R. O.

 

¹Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, Lagos, Nigeria

2Department of Medical Microbiology, Lagos University Teaching Hospital (LUTH), Lagos, Nigeria

*Correspondence to: otaruboluwatife@gmail.com; Tel: +2348140528910; ORCID: 0009-0003-9413-7832

 

Abstract:

 

Background: Carbapenem-resistant Klebsiella pneumoniae (CRKP) infections pose a major challenge due to limited therapeutic options. Biofilm formation has been proposed as a potential contributor to antimicrobial resistance; however, evidence regarding its association with carbapenem resistance in K. pneumoniae remains conflicting. Notably, data from Nigeria are scarce. The objective of this study is to compare biofilm formation between carbapenem-resistant and carbapenem susceptible K. pneumoniae (CRKP and CSKP) isolated from blood samples. Continue reading “Comparative analysis of biofilm formation in carbapenem-resistant and carbapenem-susceptible Klebsiella pneumoniae clinical isolates from a tertiary hospital in Nigeria”