Prevalence of New Delhi metallo-β-lactamase gene among multi- drug-resistant Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa clinical isolates at the University College Hospital, Ibadan, Nigeria

University College Hospital, Ibadan, Nigeria

*1,2Jugah, C. C., 1,3Makanjuola, O. B., 1Ogunleye, V. O., 4Azuh, V. O., 4Kazeem, O. S.,

1,4Subulade, A. A., 4Adesanya, O. A., 4Adeniyi, A. V, and 1,3Kehinde, A. O.

   1Department of Medical Microbiology and Parasitology, College of Medicine, University of Ibadan, Nigeria

2College of Medicine, University of Ibadan, Nigeria

3University College Hospital, Ibadan, Nigeria

4Biorepository and Clinical Virology Laboratory, College of Medicine, University of Ibadan, Nigeria  *Correspondence to: christianaokiyi25@gmail.com

 

Abstract:

Background: Failure of antimicrobial therapy may give an insight into carriage of resistance genes among microbial pathogens. The ease of spread of these genes including beta-lactamase genes such as blaNDM, blaKPC, and blaOXA-48 is a major public health challenge worldwide. The study aimed to detect New Delhi metallo-β-lactamase (blaNDM) gene carriage among multidrug-resistant (MDR) Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa isolates from clinical specimens at the University College Hospital, Ibadan (UCH), Ibadan, Nigeria. Continue reading “Prevalence of New Delhi metallo-β-lactamase gene among multi- drug-resistant Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa clinical isolates at the University College Hospital, Ibadan, Nigeria”