*¹Otaru, B. M., 2Aikhomu V., and ¹Oladele, R. O.
¹Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, Lagos, Nigeria
2Department of Medical Microbiology, Lagos University Teaching Hospital (LUTH), Lagos, Nigeria
*Correspondence to: otaruboluwatife@gmail.com; Tel: +2348140528910; ORCID: 0009-0003-9413-7832
Abstract:
Background: Carbapenem-resistant Klebsiella pneumoniae (CRKP) infections pose a major challenge due to limited therapeutic options. Biofilm formation has been proposed as a potential contributor to antimicrobial resistance; however, evidence regarding its association with carbapenem resistance in K. pneumoniae remains conflicting. Notably, data from Nigeria are scarce. The objective of this study is to compare biofilm formation between carbapenem-resistant and carbapenem susceptible K. pneumoniae (CRKP and CSKP) isolated from blood samples. Continue reading “Comparative analysis of biofilm formation in carbapenem-resistant and carbapenem-susceptible Klebsiella pneumoniae clinical isolates from a tertiary hospital in Nigeria”