Environmental contamination rates by extended-spectrum β-lactamase producing Acinetobacter baumannii in selected hospitals in southwest Nigeria

Department of Microbiology, Adekunle Ajasin University, Akungba-Akoko, Ondo State, Nigeria

Correspondence to: ayorinde.akinbobola@aaua.edu.ng

 

Abstract:

 Background: Acinetobacter baumannii poses significant threat in healthcare facilities due to its innate ability to persist on harsh environmental surfaces for extended periods and its common resistance to multiple antibiotics, through mechanisms such as extended-spectrum β-lactamase (ESBL) production. Healthcare-associated (HAI) A. baumannii infections are a growing concern in low-and-middle-income countries (LMICs), with environmental surfaces serving as important reservoirs for transmission. However, there is limited information on A. baumannii contamination rates of environmental surfaces in healthcare facilities. This study determined the contamination rates and antimicrobial susceptibility profiles of A. baumannii from high-touch surfaces in selected hospitals in Akoko area of Ondo State, southwest Nigeria. Continue reading “Environmental contamination rates by extended-spectrum β-lactamase producing Acinetobacter baumannii in selected hospitals in southwest Nigeria”

Point prevalence survey of antimicrobial consumption and resistance: 2015-2018 longitudinal survey results from Nigeria

*1Umeokonkwo, C. D., 2Oduyebo, O. O., 3Fadeyi, A., 4Versporten, A., 5Ola-Bello, O. I,  6Fowotade, A., 7Elikwu, C. J., 4Pauwels, I., 6Kehinde, A., 8Ekuma, A.,           4Goossens, H., 9Adedosu, A. N., 10Nwafia, I. N., 11Nwajiobi-Princewill, P., 2Ogunsola, F. T., 12Olayinka, A. T., and 11Iregbu, K. C.                            

1Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Nigeria

2College of Medicine/Lagos University Teaching Hospital, Lagos, Nigeria

3University of Ilorin Teaching Hospital, Ilorin, Nigeria

4Laboratory of Medical Microbiology, Vaccine and Infectious Diseases Institute, University of Antwerp, Antwerp, Belgium

5State Specialist Hospital, Akure, Nigeria

6College of Medicine/University College Hospital, Ibadan, Nigeria

7Babcock University Teaching Hospital, Ilishan-Remo, Nigeria

8University of Uyo Teaching Hospital, Uyo, Nigeria

9Federal Medical Centre, Owo, Ondo Nigeria

10University of Nigeria, Teaching Hospital Ituku-Ozalla, Enugu, Nigeria

11National Hospital, Abuja, Nigeria

12Ahmadu Bello University Teaching Hospital, Zaria, Nigeria *Correspondence to: chukwumau@gmail.com

 

Abstract:

 Background: Nigeria joined the global community in monitoring antimicrobial prescribing practices since 2015. Results of individual hospital Global Point Prevalence Survey (Global-PPS) have stimulated efforts at instituting hospital-based antimicrobial stewardship (AMS) programmes. We report the trends of antimicrobial prescribing rates and quality indicators for 3 surveillance periods; 2015, 2017 and 2018.

Methodology: The web-based Global-PPS for surveillance of antimicrobial use in hospitals (www.globalpps.com) was completed by each participating hospital site for all inpatients receiving antimicrobials on a selected day in 2015, 2017 and 2018. Data included details on antimicrobial agents, reasons and indications for treatment and a set of quality prescribing indicators. Data were validated by the web-based data management system of University of Antwerp, exported into Microsoft Excel and analyzed with EPI INFO version 7.2. Continue reading “Point prevalence survey of antimicrobial consumption and resistance: 2015-2018 longitudinal survey results from Nigeria”