*[1],[2]Olorundare, O. O., [3],4Nnadi, N. E., 1Nimzing, L., 1Ayanbimpe, G. M.
1Department of Medical Microbiology, Faculty of Basic Clinical Science, University of Jos, Plateau State, Nigeria
2Department of Pest Management Technology, Federal College of Forestry, Jos Plateau State Nigeria
3Department of Microbiology, Faculty of Natural and Applied Sciences, Plateau State University, Bokkos, Plateau State, Nigeria
4Centre for Phage Biology and Therapeutics, Jos, Plateau State, Nigeria
*Correspondence to: olufunmilolaolorundare@gmail.com; Tel: +2348069697670
Abstract:
Background: Typhoid fever, caused by antibiotic-resistant Salmonella enterica serovar Typhi (Salmonella Typhi), is a significant public health issue, especially in Nigeria, necessitating exploration of alternative treatment strategies such as the use of bacteriophages. Bacteriophages are viruses that specifically infect and replicate within bacteria and play important roles in medicine. The objective of this study is to isolate and characterize two lytic phages against S. Typhi, assess their stability under various environmental conditions and determine their potentials as biocontrol agents and alternatives to antibiotics for treatment of S. Typhi infections. Continue reading “Exploring lytic Salmonella phages as potential alternatives to antibiotics: Isolation, characterization, and stability assessment of Jerseyvirus Ijeoma and Apdecimavirus Ayanbimpe”