*[1]Ekpunobi, N. F., 1Ugwu, M. C., 2Agu, K. C., 1Chukwunwejim, C. R., 3Nedum, C. H., 1Okoye, L. C., and 1Mgbedo, U. C.
1Department of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria
2Department of Applied Microbiology and Brewing, Faculty of Biosciences, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria
3Department of Pharmacognosy and Traditional Medicine, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria
*Correspondence to: nzubefavour34@gmail.com
Abstract:
Background: Urinary tract infections (UTIs) are a significant global health concern with rising antimicrobial resistance (AMR) posing a serious challenge to effective treatment. The increasing prevalence of extendedspectrum beta-lactamase (ESBL)-producing uropathogens further complicates management, as these bacteria are resistant to third-generation cephalosporins and other β-lactam antibiotics. The objective of this study is to determine the prevalence and characterize ESBL genes in uropathogens isolated from children with UTIs in Ajeromi General Hospital, Ajegunle, Lagos, Nigeria. Continue reading “Prevalence and molecular detection of ESBL genes in uropathogens isolated from children and adolescents in a General Hospital in Lagos, Nigeria”