Multiple antibiotic resistance index

^*1Bindawa, H. A., ^2,3Abdulkadir, B., ²Rumah, H. M., and ⁴Samaila, A.

¹College of Health Sciences and Technology, Katsina, Katsina State, Nigeria ²Department of Microbiology, Umaru Musa Yar’adua University, Katsina, Katsina State, Nigeria

³Medical Laboratory Science, Umaru Musa Yar’adua University, Katsina, Katsina State, Nigeria

⁴Department of Clinical Pharmacology and Therapeutics, College of Health Sciences,

Umaru Musa Yar’adua University, Katsina, Katsina State, Nigeria *Correspondence to: hafsatbindawa96@gmail.com

Abstract:

Background: Neonatal sepsis remains a major cause of morbidity and mortality in developing countries, with

Staphylococcus aureus being one of the leading causative organisms. The rising occurrence of multidrug-resistant (MDR) strains poses significant therapeutic challenges. This study aimed to determine the antibiotic resistance pattern and multiple antibiotic resistance (MAR) index of S. aureus isolated from neonatal sepsis cases in the Special Care Baby Unit (SCBU) of a secondary healthcare facility in Katsina State, Nigeria. Continue reading “Multidrug-resistant Staphylococcus aureus associated with neonatal sepsis in the special care baby unit of a secondary healthcare facility in Katsina State, Nigeria”

^*[1],3Ukam, I. I., ³Umoh, N. O., ¹Iyam, S. O., ²Nwibari, B. M. W., ¹Ugwu, J. C., ³Ben, S. A., and ³Ogba, O. M.

¹Department of Microbiology, Faculty of Biological Sciences, University of Calabar, PMB 1115 Calabar, Nigeria

²Department of Zoology and Environmental Biology, Faculty of Biological Sciences, University of Calabar, PMB 1115 Calabar, Nigeria

³Department of Bacteriology, Virology and Mycology, Faculty of Medical Laboratory Science, University of Calabar, PMB 1115, Calabar, Nigeria

*Correspondence to: ukamjohn8@gmail.com; igborukam@unical.edu.ng; Tel: +2349074254995/ +2348032327041; ORCiD: 0009-0005-7645-5508

Abstract:

Background: The global spread of extended spectrum beta-lactamases (ESBL) and carbapenemase-producing strains of Klebsiella pneumoniae, is considered a major public health threat to humans. Antimicrobial resistance mediated by New Delhi Metallo-β-lactamase (NDM) enzyme has become a major threat to treatment outcome. This study is aimed at investigating the carriage rate of bla_NDM gene among multidrug resistant (MDR) clinical K. pneumoniae isolates from four selected health facilities in Calabar, Nigeria. Continue reading “Prevalence of New Delhi Metallo-β-lactamase gene and antibiotic susceptibility of clinical Klebsiella pneumoniae isolates from selected hospitals in Calabar, Nigeria”