nasal colonization – afrjcem.org

^*1,2Sineque, A., ¹Mabasso, A. A., ¹Chongo, A. E., and ¹Mussagy,A.

¹Department of Biological Sciences, Eduardo Mondlane University, Maputo, Mozambique

²Centre for Functional Ecology – One Health, Department of Life Sciences, University of Coimbra, Coimbra, Portugal *Correspondence to: sineque.alberto@uem.ac.mz; ORCID: https://orcid.org/0000 –0003 –2468 –9925

Abstract:

Background: Nasal colonization by Staphylococcus aureus is a major source of community and hospital associated staphylococcal infections, including methicillin-resistant S. aureus (MRSA) infections. Screening of MRSA nasal colonization is important in the prevention and control of infection and may provide useful information to guide antimicrobial therapy. The study aimed to determine the prevalence of nasal colonization by methicillin-resistant S. aureus and its glycopeptide susceptibility pattern among symptomatic and asymptomatic individuals in Maputo, Mozambique. Continue reading “Nasal colonization of methicillin and glycopeptide resistant Staphylococcus aureus among outpatients at a clinic facility in Maputo, Mozambique: A cross-sectional study”

*¹Okunbor, H. N., ¹^,²Otaigbe, I. I., ¹^,²Oluwole, T. O., ¹^,²Elikwu, C. J., and ³Bhola, A. K.

¹Department of Medical Microbiology, Babcock University Teaching Hospital, Ilishan-Remo, Ogun State, Nigeria

²Department of Medical Microbiology and Parasitology, Babcock University, Ilishan-Remo, Ogun State, Nigeria

³ISID-BMGF Research Capacity Building Mentor

*Correspondence to: okunborh@babcock.edu.ng; Tel: +2348059834262; ORCID: 0009-0001-2016-6310

Abstract:

Background: Antimicrobial resistance (AMR) among Staphylococcus aureus, particularly methicillin-resistant S. aureus (MRSA) and vancomycin-resistant S. aureus (VRSA), poses a major global public health challenge. Data on the molecular epidemiology of resistance genes in Nigeria remain limited. The objectives of this study are to determine the prevalence of mecA, vanA, and vanB genes among nasal S. aureus isolates, assess antimicrobial susceptibility profiles, and explore associations of prevalence with demographic and clinical characteristics of hospitalized patients in Babcock University Teaching Hospital (BUTH), Ilishan-Remo, Nigeria. Continue reading “Prevalence of mecA and vanA genes in nasal Staphylococcus aureus isolates from hospitalized patients in Babcock University Teaching Hospital, Ilishan-Remo, Nigeria”