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Relationship between serum viral load and stages of hepatic fibrosis in patients with chronic hepatitis C virus infections in Plateau State, Nigeria

1,2,3Maktep, Y, D., 1,2Egah, D. Z., and 1Nimzing, L.

¹Department of Medical Microbiology, Faculty of Clinical Sciences, College of Health Sciences, University of Jos, PMB 2084 Jos, Nigeria

²Department of Medical Microbiology, Jos University Teaching Hospital, Jos, Nigeria

³Department of Medical Microbiology and Parasitology, College of Health Sciences, Bingham University,  Jos Campus, Nigeria

*Correspondence to: yadangmaktep@gmail.com

Abstract

Background: Chronic hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide and remains a significant contributor to liver-related morbidity and mortality. Hepatic fibrosis is the key determinant of long-term clinical outcomes. Although viral replication is central to HCV pathogenesis, the association between serum HCV load and the severity of hepatic fibrosis remain controversial. The objective of this study is to evaluate the relationship between serum HCV load and hepatic fibrosis severity, using Transient Elastography (FibroScan), among patients with chronic HCV infection.      Continue reading “Relationship between serum viral load and stages of hepatic fibrosis in patients with chronic hepatitis C virus infections in Plateau State, Nigeria”

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Molecular epidemiology of genital Chlamydia trachomatis infections among women of reproductive age living with HIV/AIDS in a Nigerian tertiary health institution

*1,2,3Abayomi, S. A., 3Akanbi, A. A., 2Taiwo, S. S., 4Omoare, A. A., and 5Adegboro, B.

 1Cancer Research UK, Swansea, Wales, United Kingdom                                                2Department of Medical Microbiology and Parasitology, LAUTECH Teaching Hospital, Ogbomoso, Nigeria

3Department of Medical Microbiology and Parasitology, University of Ilorin Teaching Hospital, Ilorin, Nigeria

4Public Health Laboratory Services, Nigeria Centre for Disease Control and Prevention (NCDC), Abuja, Nigeria

5Department of Medical Microbiology and Immunology, Nile University of Nigeria, Abuja, Nigeria  *Correspondence to: subslaabayomi@gmail.com

Abstract:

Background: Chlamydia trachomatis is the most prevalent bacterial pathogen causing sexually transmitted infections (STIs) globally. This study investigates the genovars of genital C. trachomatis infection among women of reproductive age living with HIV/AIDS in Ilorin, Nigeria.      Continue reading “Molecular epidemiology of genital Chlamydia trachomatis infections among women of reproductive age living with HIV/AIDS in a Nigerian tertiary health institution”