*[1],[2],[3]Eliya, T. T., 1,[4]Ugwu, C., 3Jacob, P., 1Asugu, S., 5Anzaku, A. A., and 1,4,6Bimba, J.
1Zankli Research Centre, Bingham University, Karu, Km 26 Abuja-Keffi Expressway, Karu, Nigeria
2Biological Sciences Department, Bingham University, Karu, Km 26 Abuja-Keffi Expressway, Karu, Nigeria
3Stephakim Life Foundation, No. E7 Debaron Street, Nyanya Phase 4, Abuja, Nigeria
4Clinical Sciences, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom
5Institute of Human Virology, Nigeria. Plot 62, Emeritus Umaru Shehu Cadastral Zane COO, Abuja FCT, Nigeria
6Community Medicine, Bingham University, Karu, Km 26 Abuja-Keffi Expressway, Karu, Nigeria *Correspondence to: iliya.taryuta@binghamuni.edu.ng
Abstract:
Background: Tuberculosis (TB) is one of the leading causes of death worldwide, with an estimated 1.25 million people dying from TB in 2023. Most current diagnostic tests for TB rely on sputum sampling from symptomatic individuals. Sputum collection procedure involves expectoration of potentially infectious aerosols, which pose safety risks to health care workers; hence, an easier, safer, non-invasive, non-aerosol, and more effective alternative approach is warranted. This study evaluated the effectiveness and diagnostic yield of self-collected oral swab (SCOS) against sputum in detecting Mycobacterium tuberculosis (MTB) by Xpert MTB/RIF assay. Continue reading “Evaluation of self-collected oral swab sample for early detection of Mycobacterium tuberculosis by Xpert MTB assay in Karu, Nasarawa State, Nigeria”