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Preservative potentials and stability of bacteriocin-producing lactic acid bacteria of dairy origins

[1]Sangodare, A. O., *[2]Omotoso, I. O., 1Omotoso, O. G., and 3Samuel, T. A.  

 1Department of Science Laboratory Technology, Faculty of Pure and Applied Sciences, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria

2Department of Environmental Health Science, Faculty of Basic Medical Science, Ajayi Crowther University, Oyo, Oyo State, Nigeria

3Department of Microbiology, Faculty of Life Science, University of Ilorin, Ilorin, Nigeria *Correspondence to: omotosoifeoluwa@gmail.com; +2348068193274

 

Abstract:

 Background: Lactic acid bacteria (LAB) from dairy sources are known to produce bacteriocins with promising antimicrobial properties. The variations in their preservative effectiveness and stability under different environ- mental conditions create a gap in knowledge. This study aimed to produce bacteriocin and determine their stability properties of bacteriocin isolated from lactic acid bacteria indigenous to selected fermented diary (cheese and ‘Nunu’) within Ilorin metropolis.   Continue reading “Preservative potentials and stability of bacteriocin-producing lactic acid bacteria of dairy origins”

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Antibiofilm activity of plant lectins: Evaluating the anti-adhesion properties of Treculia africana, Moringa oleifera, and Allium sativum on clinical bacterial isolates

1Onyekwere, U. U., *2Eluu, S. C., 3Eluu, K., 4Aina, T., 5Enyigwe, J. O., 6Okoye, C. S., 2Nwankwo, U. V., 7Burba, R. A., 4Akinbiola, A. B., 8Oke, B., 9Ebem, E. C., and 10Eze, G. O.

1Department of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, 420110, Agulu, Anambra State, Nigeria

2Department of Biotechnology, Faculty of Science, Ebonyi State University, Abakaliki, Nigeria

3Department of Genetics and Biotechnology, Faculty of Biological Sciences, University of Calabar, Calabar, Nigeria

4Department of Biomedical Engineering, Afe Babalola University Ado-Ekiti, KM 8.5 Afe Babalola Way, Ado-Ekiti, Nigeria

5Department of Agricultural Economics, Management and Extension, Ebonyi State University, Abakaliki, Nigeria

6Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmaceutical Sciences. David Umahi Federal University of Health Sciences, Uburu, Ebonyi State, Nigeria

7Department of Family and Consumer Science, Faculty of Agriculture, Taraba State University Jalingo, Nigeria

8Applied Microbiology Department, Faculty of Science, Ebonyi State University, Abakaliki, Nigeria

9Department of Biotechnology, Alex Ekwueme Federal University, Ndufu-Alike Ikwo, Abakaliki, Ebonyi State, Nigeria

10Department of Scientific and Research Services, David Umahi Federal University Teaching Hospital, Uburu, Ebonyi State, Nigeria                                             *Correspondence to: eluustanleychijioke@gmail.com

 

Abstract:

Background: The increasing prevalence of biofilm-associated infections caused by multidrug-resistant organisms has intensified the search for alternative antimicrobial agents. This study investigated the antibiofilm activity of lectins isolated from Treculia africana leaves (TAL), Moringa oleifera leaves (MOL), and Allium sativum bulbs (ASL) against selected clinical bacterial isolates.  Continue reading “Antibiofilm activity of plant lectins: Evaluating the anti-adhesion properties of Treculia africana, Moringa oleifera, and Allium sativum on clinical bacterial isolates”

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Prevalence of vaginal Candida albicans among women attending Federal Medical Centre, Makurdi, Nigeria

1Ochekpe, O. S., 1Umeh, E. U., 1Amali, O., 1Ogbonna, I. O., 2Adikwu, P., and *2Agbo, A. A.

1Federal University of Agriculture, Makurdi, Benue State, Nigeria

2Federal University of Health Sciences, Otukpo, Benue State, Nigeria  *Correspondence to: ustynameh@gmail.com

 

Abstract:

Background: Candida albicans accounts for the most common type of opportunistic fungal infection affecting human heath globally, with more than a billion cases annually. The prevalence is reportedly high in resource-limited settings. The aim of this study is to determine the prevalence of vaginal C. albicans among women attending Federal Medical Centre, Makurdi, Nigeria.   Continue reading “Prevalence of vaginal Candida albicans among women attending Federal Medical Centre, Makurdi, Nigeria”

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Prevalence of pulmonary mycoses among patients with suspected pulmonary tuberculosis at the Infectious Disease Hospital, Kano, Nigeria

*Salim, A. B., and Nabila, M. I.

Department of Microbiology, Faculty of Life Sciences, Bayero University, Kano, PMB 3011, Kano, Nigeria

*Correspondence to: ahmadbsalim@gmail.com; +2348033731917

Abstract:

Background: Opportunistic fungal infections have been implicated among patients with tuberculosis (TB). Coexistence of pulmonary mycoses and pulmonary TB is of public health concern as they exhibit similar clinical manifestations among infected patients, which contributes to increased misdiagnosis and makes management difficult, especially in TB-prone regions like Kano, Nigeria. Thus, this study was aimed at determining the prevalence of pulmonary mycoses among patients with suspected pulmonary TB attending the Infectious Disease Hospital (IDH), Kano State, Nigeria.                                                Continue reading “Prevalence of pulmonary mycoses among patients with suspected pulmonary tuberculosis at the Infectious Disease Hospital, Kano, Nigeria”

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Relationship between serum viral load and stages of hepatic fibrosis in patients with chronic hepatitis C virus infections in Plateau State, Nigeria

1,2,3Maktep, Y, D., 1,2Egah, D. Z., and 1Nimzing, L.

¹Department of Medical Microbiology, Faculty of Clinical Sciences, College of Health Sciences, University of Jos, PMB 2084 Jos, Nigeria

²Department of Medical Microbiology, Jos University Teaching Hospital, Jos, Nigeria

³Department of Medical Microbiology and Parasitology, College of Health Sciences, Bingham University,  Jos Campus, Nigeria

*Correspondence to: yadangmaktep@gmail.com

Abstract

Background: Chronic hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide and remains a significant contributor to liver-related morbidity and mortality. Hepatic fibrosis is the key determinant of long-term clinical outcomes. Although viral replication is central to HCV pathogenesis, the association between serum HCV load and the severity of hepatic fibrosis remain controversial. The objective of this study is to evaluate the relationship between serum HCV load and hepatic fibrosis severity, using Transient Elastography (FibroScan), among patients with chronic HCV infection.      Continue reading “Relationship between serum viral load and stages of hepatic fibrosis in patients with chronic hepatitis C virus infections in Plateau State, Nigeria”

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Integron-mediated multidrug resistance in uropathogenic Escherichia coli isolates from intensive care unit: Molecular evidence from Iran within a Global Surveillance Framework

Ebtehaj Pishva Independent Researcher (Allied Health Assistance), Sydney, Australia

Correspondence to: ebtehajpishva2015@gmail.com

Abstract:

Background: Integrons are genetic platforms that facilitate acquisition and expression of antimicrobial resistance gene cassettes. Their contribution to multidrug resistance (MDR) among intensive care unit (ICU) uropathogenic Escherichia coli (UPEC) is of increasing concern. This study determined the prevalence of class 1 and class 2 integrons among ICU UPEC isolates and examined their association with resistance phenotypes. Continue reading “Integron-mediated multidrug resistance in uropathogenic Escherichia coli isolates from intensive care unit: Molecular evidence from Iran within a Global Surveillance Framework”

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Spectrum of bacterial uropathogens and their antibiotic susceptibility among patients with chronic kidney disease in a tertiary hospital, northcentral Nigeria

1Abdullahi, A. J., 2Babaita, K. A., *2Ogunniyi, T. J., 3Oyedepo, D. S., and 1Akanbi II, A. A.

1Department of Medical Microbiology and Parasitology, Faculty of Basic Clinical Sciences, University of Ilorin, Ilorin, Nigeria

2Department of Medical Microbiology and Parasitology, University of Ilorin Teaching Hospital, Ilorin, Nigeria

3Department of Nephrology, University of Ilorin Teaching Hospital, Ilorin, Nigeria

*Correspondence to: josephtolulopeogunniyi@gmail.com

Abstract:

Background: Chronic kidney disease (CKD) is increasingly recognized as a global public health problem. CKD patients are prone to comorbidities, such as diabetes mellitus, urinary tract infection (UTI), hypertension, immunesuppression, anaemia, malnutrition, inflammation, and vitamin deficiencies. However, UTI is known to be the most significant cause of morbidity and mortality in CKD patients. Therefore, this study aimed to identify the spectrum of uropathogenic bacteria in patients with CKD at the University of Ilorin Teaching Hospital (UITH), Ilorin, and determine their susceptibility to selected antibiotics.    Continue reading “Spectrum of bacterial uropathogens and their antibiotic susceptibility among patients with chronic kidney disease in a tertiary hospital, northcentral Nigeria”

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Prevalence and identification of microbial contaminants of reusable plastic containers from informal food vending sites in Calabar, Nigeria

*[1]Usang, A., [2]Omeh, B. A., and [3]Ekuma, V. O.

1Faculty of Medical Laboratory Science, University of Calabar, PMB 1115, Calabar, Nigeria

2Department of Medical Laboratory Science, College of Health Technology, Calabar, Nigeria

3Department of Parasitology and Entomology, University of Calabar, Nigeria *Correspondence to: akedorusang2rue@gmail.com

 

Abstract

 Background: Reusable plastic containers are widely used in informal food vending sites in developing countries like Nigeria, posing potential risks for microbial contamination and foodborne illnesses. This study determined the prevalence and identify microbial contaminants in 350 reusable plastic containers sampled from selected sites (markets, schools, roadside sellers, hawkers, and motor parks) in Calabar, Nigeria. Continue reading “Prevalence and identification of microbial contaminants of reusable plastic containers from informal food vending sites in Calabar, Nigeria”

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Discovery of potential antiviral compounds against Dengue virus using virtual screening and physicochemical profiling from zinc database

1Ramdeen, S. J., 1Usoro, N., 1Giordano, K., 1Garza, P. E., 2Quadri, O., 3Esan, T. E., and *1Olanrewaju,A. A.

 1Texas State University, Medical Laboratory Science Program San Marcos, TX USA

2Northern Illinois University, Chemistry and Biochemistry Analytical Lab, Dekalb, IL USA

3Rosalind Franklin University of Medicine and Science, Chicago, IL USA

*Correspondence to: dep112@txstate.edu; Phone: +1 571-228-0537

Erratum to: Afr. J. Clin. Exper. Microbiol. 2026; 27 (2): 126-133. https://dx.doi.org/10.4314/ajcem.v27i2.1

A publication error in the name of author, Quadri, P., in the previously published version of this article has been appropriately corrected as Quadri, O., in this authors page. All information in the previously published article remained valid.

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Prevalence and predictors of hepatitis B screening among pregnant women attending antenatal clinics in three primary health centres in Abeokuta, Nigeria: A cross-sectional study

*Olatunji, O. A., Fowotade, A., and Omoruyi, E. C.

Department of Medical Microbiology, University College Hospital (UCH), Ibadan, Nigeria

*Correspondence to: aliu_my2004@yahoo.com

Corrigendum to: Afr. J. Clin. Exper. Microbiol. 2026; 27 (1): 46-53 https://dx.doi.org/10.4314/ajcem.v27i1.7

An error by the authors in a previously published version of this article with respect to arrangement of authors names, has been appropriately corrected in this authors page. All information in the previously published article remained valid.

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