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^[1]Nkasa, H. L., ^[2]Kabena, O., *²Ngbolua, J. K., ³Matafwari, Z.  L., ³Ndamba, P. M.,  ^4,5Lunguya, O. M., ⁶Ambimani, C. I., ¹Mifundu, M., ¹Mulenga, M. C.,         ¹Malongwe, K. J., ¹Kayembe, S. J., and ¹Taba, K. M.

¹Department of Chemistry, Faculty of Science, University of Kinshasa, Democratic Republic of the Congo

²Department of Biology, Faculty of Science, University of Kinshasa, Democratic Republic of the Congo

³Higher Institute of Medical Technology of Kinshasa, P. O. Box 774 Kinshasa XI Section: Laboratory Technical, Democratic Republic of the Congo

⁴Department of Medical Biology, Faculty of Medicine, University of Kinshasa, Democratic Republic of the Congo

⁵National Institute of Biomedical Research, Kinshasa, Democratic Republic of the Congo

⁶Higher Pedagogical Institute of Isiro, Democratic Republic of the Congo                                            *Correspondence to: jpngbolua@unikin.ac.cd

Abstract:

Background: Mathesia is a hydro-alcoholic emulsion, colourless and somewhat viscous, based on extracts of medicinal plants and containing saponins, polyphenols, tannins, and reducing sugars. In this study, we proposed to carry out an in vitro study of the antibacterial activity of phytomedicine Mathesia on strains of bacteria isolated from diabetic foot ulcers and chronic wounds of patients in care in the University Clinics and the Hospital Centre of Mont Amba in Kinshasa, Democratic Republic of the Congo. Continue reading “In vitro antimicrobial activity of Mathesia® on bacterial isolates of wound infections in University Clinics and Hospital Centre of Mont Amba, Kinshasa, Democratic Republic of the Congo”

*^[1]Mohammed, A., ¹Ahssana, H. J., ¹Balogu, T. V., ¹Mohammed, I. L., ^[2]Badeggi U., M., and ^[3]Suleiman Mohammed.  

¹Department of Microbiology, Faculty of Natural Science, Ibrahim Badamasi Babangida University, Lapai, Niger State, Nigeria

²Department of Chemistry, Faculty of Natural Science, Ibrahim Badamasi Babangida University, Lapai, Niger State, Nigeria

³Faculty of Science, Gombe State University, Gombe, Nigeria

*Correspondence to; ibrahimnusaiba2@gmail.com; abdmohammed@ibbu.edu.ng

Abstract:  

Background: The decline in the effectiveness of common antibiotics is due to microbial resistance and has sparked research interest in discovering new antimicrobial agents from plants. The objective of this study was to evaluate the effectiveness of clove extracts on selected pathogenic bacteria and identify the active antibacterial components. Continue reading “Bioactive components of Syzygium aromaticum bud and their effects on selected pathogenic bacteria”

In January, 2023, the Science and

Security Board of the Bulletin of the Atomic Scientists moved the hands of the Doomsday Clock forward to 90s before midnight, reflec- ting the growing risk of nuclear war (1). In August, 2022, the UN Secretary-General, Ant- ónio Guterres, warned that the world is now in “a time of nuclear danger not seen since the height of the Cold War” (2). Continue reading “Editorial: Reducing the risks of nuclear war—the role of health professionals”

^*1Uchendu, J. O., ²Yovwin, D. G., and ³Esemuede, O.

 ¹Department of Histopathology/Morbid Anatomy, Delta State University, Abraka, Nigeria

²Department of Family Medicine, Delta State University Teaching Hospital, Oghara, Nigeria

³Department of Obstetrics and Gynecology, Delta State University Teaching Hospital, Oghara, Nigeria *Correspondence to: ojlinksent@gmail.com; +234 (0) 8038732062

Abstract:

Tuberculosis (TB) is a chronic granulomatous infectious pulmonary and systemic disease caused mostly by members of the Mycobacterium tuberculosis complex (MTBC). It has variable clinical presentation and is a major cause of morbidity and mortality in the middle-and-low-income-countries (LMICs). Isolated axillary tuberculous lymphadenitis (ATL) is rare and is defined as the presence of axillary tuberculous lymphadenitis in the Continue reading “Isolated axillary tuberculous lymphadenitis in a Nigerian female: A case report with review of the literature”

*^[1]Obaro, H. K., ^[2]Suleiman, M. B., ²Yekinni, S. A., Sanda^[3], A., and ^[4]Aminu, B. T.

¹Department of Microbiology, Umaru Musa Yar’adua University, Katsina, Nigeria

²Department of Paediatrics, Federal Teaching Hospital, Katsina, Nigeria

³Department of Clinical Microbiology, Federal Teaching Hospital, Katsina, Nigeria

⁴Department of Internal Medicine, Federal Teaching Hospital, Katsina, Nigeria *Correspondence to: obarohasan@yahoo.com; +2348136436916

Abstract:

Neonatal sepsis is a significant cause of neonatal morbidity and mortality, predominantly in developing countries. The bacterial causes of neonatal sepsis and their antimicrobial susceptibility patterns are however dynamic. Globicatella sanguinis is a streptococcus-like bacterial agent capable of causing serious infection in humans that has been rarely isolated from clinical samples, and is an uncommon pathogen that is difficult to identify. Continue reading “Isolation of Globicatella sanguinis from a neonate with sepsis using BacT/Alert and VITEK-2 compact system at Federal Teaching Hospital, Katsina, northwest Nigeria: A case report”

^1,2Nwankwo, C. G., ³Obazee, Y. D., ¹Sanni, E. O., ^4,5Ezike, N. K., ^*6Adegboro, B., and ⁷Asalu^., A. F.

¹Department of Haematology and Transfusion, Nile University of Nigeria, Abuja, Nigeria

²Department of Haematology and Transfusion, Asokoro District Hospital, Abuja, Nigeria

³Medical Laboratory/Blood Banking Service Unit, Asokoro District Hospital, Abuja, Nigeria

⁴Department of Anatomic Pathology and Forensic Medicine, Nile University of Nigeria, Abuja, Nigeria

⁵Department of Anatomic Pathology and Forensic Medicine, Asokoro District Hospital, Abuja, Nigeria

^*6Department of Medical Microbiology and Immunology, Nile University of Nigeria, Abuja, Nigeria

⁷Department of Clinical Pharmacology and Therapeutics, Nile University of Nigeria, Abuja, Nigeria

*Correspondence to: boazadegboro@gmail.com; boaz.adegboro@nileuniversity.edu.ng; +2348033812348

 

Abstract:

 Background: Blood transfusion saves lives, but it is associated with many complications which include transfusion transmissible infections (TTIs). The major objectives of this study were to determine; the prevalence of TTIs in the blood donated at Asokoro District Hospital, Abuja, Nigeria from 01 January to 31 December 2019; investigate the accuracy of rapid immunochromatographic (ICT) tests for preliminary TTIs screening of blood donors’ samples and confirmed by ELISA test; and establish baseline data that will provide the impetus for improvement in equipment, infrastructure, and health system management, with the ultimate goal of ensuring safer blood transfusion practice. Continue reading “Seroprevalence of transfusion transmissible infections by ELISA in donors testing negative with rapid ICT in Asokoro District Hospital, Abuja, Nigeria”

^*1,2Oshun, P. O., ^1,2Salu, O. B., and ^1,2Omilabu, S. A.

Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, Nigeria

Centre for Human and Zoonotic Virology, College of Medicine, University of Lagos, Nigeria

*Correspondence to: sampydee@yahoo.com

 

Abstract:  

 Background: Worldwide, an estimated 58 million people have chronic hepatitis C virus (HCV) infection, with about 1.5 million new infections occurring per year. About 2.3 million people living with HIV globally have serological evidence of past or present HCV infection. The aim of this study was to determine the prevalence of active HCV infection and associated risk factors among HIV positive patients attending the HIV clinic, Lagos University Teaching Hospital (LUTH), Idi-Araba, Lagos, Nigeria. Continue reading “Prevalence and risk factors for hepatitis C virus infection among HIV positive patients at the Lagos University Teaching Hospital, Nigeria”